固本通络方治疗2型糖尿病冠心病稳定型心绞痛的临床探究.pdfVIP

提 要 目的：观察固本通络方治疗2 型糖尿病冠心病稳定型心绞痛的临床疗效，并初步 探讨其发生作用的机制与目前的进展研究。方法：随机选择 60 例 2 型糖尿病冠心病 稳定型心绞痛脾肾两虚，痰浊阻滞证患者，随机分为A、B两组，每组30例。A 组为 治疗组，服用达美康 30mgQD，加用固本通络方；B 组为对照组，服用芪参益气滴丸 0.5gTid，以及服用达美康 30mQD。治疗周期为两个月。结果：中医症状总疗效，治 疗组总有效率为 93.3%，对照组总有效率为 70%，治疗组优于对照组（P＜0.05），稳 定型心绞痛有效率，治疗组总有效率为 90%，对照组总有效率为 73.3%，治疗组优于 对照组（P＜0.05），24h动态心电图疗效指标示，心肌缺血、心肌耗氧量及冠状动脉 张力均改善，治疗组优于对照组（P＜0.05），结论：固本通络方能够显著改善2型糖 尿病冠心病脾肾两虚，痰浊阻滞患者的临床症状与部分实验室指标，具有较好的临床 效果，能够显著改善患者的生存质量。固本通络方为2型糖尿病冠心病稳定型心绞痛 患者小血管病变的改善，即非介入治疗适应症的治疗和稳定型心绞痛的防治提供了新 的思路和方法。 关键词 固本通络方； 2型糖尿病冠心病； 稳定型心绞痛；脾肾两虚，痰浊阻 滞；临床研究 Gubentongluofang to the treatment of stable angina pectoris in Coronary heart disease with type 2 DM clinical research Speciality: Medicine of TCM Tutor: Prof.Bao Pei rong Author: Sunliang Abstract Objective: To observe the clinical effect of gubentongluofang to the treatment of type 2 DM with coronary heart disease with stable angina and to investigate its mechanism and the role of the current progress. : Then select 60 patients with type 2 diabetes with coronary heart disease with stable angina pectoris spleen and kidney deficiency phlegm block Syndrome, were randomly divided into two groups (A, B), 30 cases in each group. Group A for the treatment group taking to Diamicron 30mgQD, gubentongluofang. Group B as the control group, qishenyiqidiwan 0.5g Tid, as well as taking the Diamicron 30mgQD. The treatment cycle for two months. Results: The total efficacy of TCM symptoms, treatment group, the total effective rate was 93.3%, control group, the total effective rate was 70%, the treatment group than the control group (P0.05), stable angina pectoris efficiency, the treatment group, the total efficiency 90%, control group, the total effective rate was 73.3%, the treatme