窦性心律震荡现象对慢性充血性心力衰竭的临床意义探讨.pdfVIP

[摘要1 目的 探讨窦性心律震荡现象对慢性充血性心力衰竭患者的临床意义。 方法 测定和比较98例心力 衰竭患者和100例健康人室性期前收缩后的震荡初始(TO)和震荡斜率(TS)值。 结果 心力衰竭组TO(O．13％± 0．19％)高于对照组(一0 03％±0．12％)，TS(2 29±0 62／ms／R—R)低于对照组(3 15±0 91／ms／R—R)．差异均有非 常显著性意义(PO 01 o经2±0．5年随访发现患者死亡率以TO和TS均异常组最高．TO或TS不正常组次之，差异 均有非常显著性意义(PO．01)。 结论 心力衰竭患者窦性TO和 ／或TS值异常时死亡率增高，及时观察其TO和 TS值对检出猝死高危患者并进行干预治疗具有重要的临床意义。 [关键词1慢性充血性心力衰竭； 心律震荡 【中图分类号】R540．4 1；R541．7+5 【文献标识码】A 【文章编号】 1002—1094(2008)01—0070—03 Clinical Significance of Heart Rate Turbulence in Patients with Chronic Heart Failure CHEN Hong，ZHENG Mimg— fo g Department rJ厂Electrocardiogram，Putuo Traditional Chinese Medial Hospital，Zhoushart，Zhejiang,316100，China Department of Electrocardiogram，Zhoushan People S Hospita1) Corresponding author：CHEN Hong，E—mail：chenhongdoctor@yahoo．COBt．cn [Abstract1 Objective To investigate clinical significance of heart rate turbulence in patients with chronic heart failure(CHF) Methods Turbulence onset(TO)and turbulence slope(TS)were measured and compared between 98 cases with CHF(CHF group)and 1O0 subjects with ventricular extrasystole(control group) Results TO was higher and TS was lower in CHF group(O．13％±0．1 9％．2．29 4--0．62／ms／R—R)than that in control group(一0．03％± 0．12％，3．15±0．91／ms／R-R)．The difference between them was significant(both PO 01)．During a follow—up of 2±0 5 years．mortality was highest in patients with both abnormal TO and TS，and higher in patients with either of abnormaI T0 and TS than lhal n patients with normaI T0 and TS． Conclusion Mortality ncreases in patients with abnormal TO and／or TS．Measurements of TO and TS maybe benefit to prediction and prevention of sudden death in patients with CHF． [Key words1 Chronic heart fallure； Heart rate turbulence 慢性充血性心力衰竭(下称心力衰竭)患者是 患者进行窦性心律震荡的检测，以探讨该项指标对 心脏性猝死的高危人群，对其进行危险分层及死亡 心力衰竭患者的临床意义。 率的预测，进而采取干预性治疗，一直是受临床关注 资料和方法