益气通络汤干预糖尿病肢体动脉闭塞症ABI的临床探究.pdfVIP

提 要 目的：通过益气通络汤对糖尿病肢体动脉闭塞症踝肱指数（Ankle-Brachial Index ，ABI ）进行干预的临床研究，探讨糖尿病肢体动脉闭塞症的早期治疗及疗效， 以减少糖尿病性坏疽及截肢的发生率。方法：将 60 例气虚血瘀型糖尿病肢体动脉闭 塞症患者随机分为治疗组和对照组，治疗组服用益气通络汤，对照组服用糖脉康颗粒， 疗程均为 4 个月。观察两组患者治疗前后踝/肱指数、临床症状、血脂、纤维蛋白原 等指标的变化。结果：两组患者的踝/肱指数、临床症状、血脂、纤维蛋白原等均有 了明显改善。两组患者踝肱指数、临床症状、血脂等指标比较有统计学意义 （P0.05 ）， 治疗组疗效优于对照组。临床试验期间未发现明显不良反应。结论：益气通络汤可以 提高糖尿病肢体动脉闭塞症患者的 ABI 水平，改善患者的临床症状，达到早期防治 糖尿病肢体动脉闭塞症的效果，减少坏疽及截肢的发生。 关键词 糖尿病肢体动脉闭塞症 益气通络汤 踝肱指数 临床研究 The clinical research of YiQiTongLuoTang in interfering the Ankle-Brachial Index of Diabetic Arterial Occlusion of Lower Extremities Speciality: Clinical medicine of TCM Author: zhang xiao lin Tutor: Professor Zhang Juan Abstract Objective:By the clinical research of YiQiTongLuoTang in interfering the Ankle-Brachial Index of Diabetic Arterial Occlusion of Lower Extremities （DAO ）,to explore the early treatment and effection of DAO and reduce the incidence rate of diabatic gangrene and amputation. Methods :60 patients who suffered from DAO were randomly divided into two groups including the treatment group and the control group.The treatment group was given YiQiTongLuoTang,while the control group was given TangMaiKang granule.4 months later,we observed the change of ankle-brachia Index,clinical symptom,blood-fat index,fibrinogen between the treatment group and the control group.Results:The two groups ′ ankle-brachia Index, clinical symptom,blood-fat index,fibrinogen were obviously improved. There was significant difference between the treatment group and the control group （P ＜0.05 ）and the effect of the treatment group was better than the control