益肾活血方治疗肾虚血瘀型卵巢储备功能下降性月经后期、过少的临床探究.pdfVIP

提 要 目的：观察益肾活血方治疗肾虚血瘀型卵巢储备功能下降性月经后期、过少的疗 效，并探讨其作用机理。 方法：采取随机数字表法，将 61 例肾虚血瘀型卵巢储备功能下降性月经后期、 过少的患者，分为治疗组31例（服用益肾活血方），对照组 30例（服用坤灵丸），观 察治疗前后两组患者月经周期、月经血量、经质三大主症及其它临床症状的改善情况， 以及治疗前后血基础FSH、LH、FSH/LH、E 水平的变化。 2 结果：治疗后两组患者中医证候评分组间比较有非常显著性差异(P0.01)；治疗 后两组患者FSH、LH、FSH/LH水平较治疗前均有下降，E2 水平较治疗前均有上升，组 内比较有非常显著性差异(P0.01)，组间比较有显著性差异(P0.05)。 结论：益肾活血方治疗肾虚血瘀型卵巢储备功能下降性月经后期、过少疗效显著。 其机理可能与益肾活血方可改善子宫、卵巢组织的血液循环和供应，提高卵巢中各级 卵泡的数量及卵泡质量，促使颗粒细胞产生更多的抑制素，从而降低FSH、LH、FSH/LH 水平，提高 E 水平，还可以促使卵巢发育，从而提高卵巢功能以达到调经及改善临 2 床症状的疗效。 关键词 益肾活血方；卵巢储备功能下降；肾虚血瘀；月经后期、过少；临床研 究 The Clinical Research of Yishenhuoxue Fang in Treating Kidney Deficiency and Blood Stasis Menopathy result from declining ovarian reserve Speciality: Gynecology of Traditional Chinese Medicine Tutor: Professor Ye Qing Author: LiuFanXing Abstract Objective: To observe the Yishenhuoxue Fang treatment of kidney deficiency and blood ovarian reserve decline in the late menstruation, and too little effect and explore its mechanism. Methods: select 61 cases of kidney deficiency and blood stasis ovarian reserve decline in the late menstruation, fewer patients, take random number table,.the treatment group, 31 cases (taking Yishenhuoxue Fang), 30 patients (taking Kun Ling Wan), observe curative effects of the two groups before and after the treatment.The menstrual cycle, amount, by the improvement of the quality of the three main symptoms and systemic symptoms ,blood basis of FSH, LH, FSH / LH and E level changes after treatment. 2 Results: After treatment, TCM symptoms score between groups of very significant difference (P 0.01); the levels of