糖及汤治疗高血压合并IGT的临床研究.pdfVIP

提 要 目的：本研究旨在探讨在缬沙坦治疗的基础上加用益气健脾、补益肝肾的中药 方糖和汤能否更好的控制血压、血糖并降低此类患者发展为糖尿病的危险性。方 法：60例患者随机分成两组，两组均采用缬沙坦作降压基础治疗，治疗组(30例)加服 糖和汤，并简单告知患者饮食与运动的注意事项；对照组(30例)予以严格的生活方式 干预，观察两组治疗前后临床症状、体征和实验室检查指标的变化。结果：1.治疗组 综合疗效总有效率为90%，对照组为73.33%，两组间比较有差异性(P0.05)。2.治疗 组中医症状改善总有效率为90%，对照组为63.33%，两组间比较有差异性(P0.05)。 3.糖和汤在降低血糖与糖化血红蛋白、改善血脂与胰岛素抵抗方面均有较好的疗效， 且组间比较有差异性(P0.05) 4.糖和汤在协助降压、降低BMI和腰围方面均有较好的 疗效，治疗前后比较有显著差异(P0.05)，但组间比较无差异性(P0.05)。结论：本 研究丰富了中医药治疗高血压合并IGT的理论内容，肯定了糖和汤“益气健脾，补益 肝肾”的临床疗效，为今后深入研究奠定了基础。 关键词 益气健脾，补益肝肾；糖和汤；缬沙坦；生活方式干预；高血压合并IGT Clinical research on high blood pressure combined IGT treated with replenishing qi to invigorate the spleen, tonifying the liver and kidney Speciality：Internal medicine of Traditional Chinese Medicine Author ：Wang Liang Tutor ：Prof.Xu Yunsheng Abstract Objective:This study aimsed to explore whether that on the basis of valsartan in the treatment of combined with traditional Chinese medicine TangHeTang of replenishing qi to invigorate the spleen, tonifying the liver and kidney could better control blood pressure, blood sugar and reduce the risk of such patients’ development towards diabetes mellitus. Methods: 60 patients were randomly divided into two groups which were made of valsartan antihypertensive therapy, the treatment group (30 cases) took TangHeTang and patients were simply informed considerations about diet and exercise. The contrast group (30 cases) would adopt a strict lifestyle intervention, clinical symptoms were observed before and after treatment, including signs and laboratory indices.Result: 1. the total effect rate of TangHeTang treatment group was 90%,the effect rate of the contrast group was 73.33%,there were a remarkable difference