口腔 药理学0101（Oral pharmacology 0101）.docVIP

口腔 药理学0101（Oral pharmacology 0101） Contact occurred around l0 days. Common in allergic patients. The nature of the reaction was independent of the original effect of the drug, and the rational antagonist was ineffective. The severity of the reaction varies greatly from dose to dose, from minor rash, fever to hematopoietic suppression, liver and kidney dysfunction, shock, etc.. After the withdrawal, the reaction gradually disappears and may be reused later. - (outline of idiosyncratic reaction does not require, as compared to here) A few specific physical patients for certain drug reactions particularly sensitive reaction properties may also be different from ordinary people, but the pharmacological effects and drug inherent consistent reaction severity and dose proportional pharmacological antagonists may be effective treatment. Its not immune. No pre sensitization process is required. Is a kind of congenital anomalies caused by the reaction, such as loose idiosyncratic reaction occurred on drug succinylcholine muscle due to congenital deficiency of plasma cholinesterase. Original table: - pharmacological allergy and idiosyncratic reaction comparison table The relationship between the cause and dose of the population, whether the immune response, skin test can prevent the antagonist A drug that is independent of the drug itself, metabolism, or impurities A few patient drug idiosyncrasy idiosyncratic reaction itself cannot possibly not effective [supplementary knowledge: what is the receptor? (used only for comprehension, syllabus not required) Is a kind of functional protein receptor mediated signal transduction, can trace some chemical identification in the surrounding environment, and combined with the first, and through the intermediary information amplification system, triggering subsequent physiological responses or pharmacological effects. With five receptor: The sensitivity of the receptor to a very low concentration of ligand binding can produce a significa