肿瘤相关性抑郁、焦虑发病率和相关因素的临床调查.pdf

提 要 目的：通过对山东中医药大学附属医院213 例恶性肿瘤住院患者情况的分析，探 讨恶性肿瘤患者肿瘤相关性抑郁、焦虑的发病情况及影响因素，为临床治疗提供借鉴。 方法：对住院患者进行问卷式临床调查，采用 SPSS17.0 软件进行数据统计，分 析恶性肿瘤住院患者肿瘤相关性抑郁、焦虑的发病情况及各因素对抑郁、焦虑发病率 的影响，找出中医证型和肿瘤相关性抑郁、焦虑发病的相关性及影响患者肿瘤相关性 抑郁、焦虑发病的独立危险因素。 结果：肿瘤相关性抑郁发病率为46% ，其中中度抑郁发病率为 18.3%，未发现重 度抑郁者；肿瘤相关性焦虑发病率为 16.4%，其中中度焦虑发病率为 6.6%，未发现 重度焦虑者。肿瘤相关性抑郁与肿瘤发病部位、肿瘤家族史、居住地无关（P ＞0.05）， 与性别、年龄、肿瘤分期、中医辨证分型、慢性癌痛、KPS 评分、化疗方案种类、治 疗副作用、知情情况、费用负担方式、文化程度、收入相关（P＜0.05），其中性别、 中医辨证分型、肿瘤分期、既往化疗史、知情情况、慢性持续性疼痛、KPS 评分等 7 个为独立危险因素。中医辨证分型中气郁化火、肝气郁结、痰气郁结发病率依次为 95%、92.1%、61.2% 。 结论：肿瘤相关性抑郁、焦虑临床发病率较高，对女性、中晚期、有多次化疗史、 KPS 评分低、伴慢性癌痛者，应重视其心理状况，及时发现并诊断治疗，以提高患者 生存质量。 关键词 肿瘤相关性抑郁、焦虑；发病率；影响因素 Clinical investigation the incidence of cancer-related depression, anxiety and the related factors Specialty：Clinical internal medicine of TCM Western medicine Student：Sun haiyan Tutor：Prof. Qi yuanfu Abstract Objective: By analyzing the 213 cases of malignant tumors from the Affiliated Hospital of Shandong University of Traditional Chinese Medicine hospitalized patients, to explore the incidence of malignant tumors in patients with cancer-related depression, anxiety and affect the incidence of relevant factors to provide a reference for clinical treatment. Methods: Inpatients are investigated by questionnaire, and SPSS17.0 statistical software for data analysis, analysis incidence and the factors on the incidence of cancer-related depression and anxiety of hospitalized patients, and identify TCM syndrome and cancer-related depression and anxiety, and identify independent risk factors for patients with cancer-related depression, anxiety. Results: The incidence of cancer-related depressi