补肾调经方治疗卵巢早衰肾阴阳两虚证的临床探究.pdfVIP

提 要 目的：观察补肾调经方治疗卵巢早衰肾阴阳两虚证各项临床症状的改善,并探讨 相关作用机理。 方法：共观察卵巢早衰患者 42 例，治疗组 21 例，服用补肾调经方；对照组 21 例，服用佳蓉片，观察两组患者临床症状改善情况及对卵泡刺激激素FSH、黄体生成 素LH、雌激素 E 、B超、BMD值的影响。 2 结果：两组患者治疗后中医症状总积分，治疗组与对照组相比有显著性差异（P 0.05）；两组患者疗后卵泡刺激素、黄体生成素较治疗前明显降低，组内比较有非常 显著性差异（P 0.01），组间比较有显著性差异（P 0.01或 P 0.05）。两组患者治 疗后血清 E 、BMD、卵巢最大直径均较前升高，组内比较有非常显著性差异 （P0.01）， 2 组间比较有显著性差异（P0.05）。 结论：补肾调经方治疗卵巢早衰有较好疗效，患者各项临床症状有明显改善。其 机理可能与补肾调经药物可改善内分泌水平，提高患者体内 E2 水平，降低 FSH、LH 水平等有关。 关键词 卵巢早衰；补肾调经；临床研究 The Clinical Research on the Effect of Bu Shen Tiao Jing Fang in Treating Premature ovarian failure Speciality: Gynecology of TCM,The study of menstruation sickness and sterility Tutor: Professor Ye Qing Author: Huang Yunxia Abstract Objective：Observe the clinical curative effect of Bu Shen Tiao Jing Fang ，which is applied to treat POF, and explore its work mechanism. Methods: We totally observed 42 patients of POF and it was divided into two groups randomly. The treatment group take Bu Shen Tiao Jing Fang, while the control group takes Jiarongpian，which are compared to observe their curative effects and impacts on Follicle stimulating hormone （FSH ） Luteinizing hormone (LH) 、Estrogen hormone （E2 ）、 Biggest diameter ovarian under Btype ultrasonic and Bone mineral density(BMD). Results: After treatment, the syndrome score of the two groups has significant differences (P 0.01). The FSH level and the LH level of the two groups are both obviously decreased after treating, which has significant differences compared with its original level (P 0.01) and the control group (P 0.01 or P0.05). The E level 、 BMD