补肾调肝活血汤治疗肾虚肝郁型育龄期多囊卵巢综合征的临床视察.pdfVIP

提 要 目的：观察补肾调肝活血汤治疗肾虚肝郁型育龄期多囊卵巢综合征（PCOS ）的 临床疗效，探讨其作用机理，以期为中医治疗 PCOS 寻找更有效的方法。方法：将 60 例证属肾虚肝郁型育龄期 PCOS 患者随机分为 2 组，治疗组 30 例，口服补肾调肝 活血汤及克罗米芬（cc ）；对照组 30 例，口服克罗米芬（cc ）。观察治疗前后 3 个月 临床表现、月经改善及妊娠情况、中医症候改善，血清卵泡刺激素（FSH ）、黄体生 成素（LH ）及其两者的比值、睾酮（T ）、雌激素（E ）、胰岛素（INS ）的含量及 B 2 超变化。结果： 治疗组可有效改善肾虚肝郁的症候；改善月经、不孕、座疮、卵巢 体积等临床症状及体征。可显著降低 PCOS 患者血清 LH 、T、INS 水平，升高 E2 水 平，改善 LH/FSH 比值，统计学分析优于对照组（P0.05 ）。治疗组总有效率为90.00 ％，排卵率 86.67 ％，妊娠率为 50.00 ％；对照组总有效率 63.33 ％，排卵率为 60.00 ％，妊娠率为23.33 ％。两组比较差异均有显著性（P0.05 ）。结论：在西药基础上加 上补肾调肝活血汤治疗育龄期肾虚肝郁型 PCOS 患者，能有效改善内分泌紊乱及临床 症状，重建月经和排卵周期、提高妊娠率，疗效优于西药组。 关键词 补肾调肝活血汤；多囊卵巢综合征；育龄期；肾虚肝郁 The Kidney and Liver Soup Treatment Kidney Empty Stomach Tone of Childbearing Age-to Clinical Observation of Polycystic Ovarian Syndrome Specility: Gynecology of Traditional Chinese Medicine Author: Cai Xiaohui Tutor: Professor Wu Xinhua Abstract Objective: to observe the kidney and liver soup treatment kidney empty stomach tone of childbearing age-to polycystic ovarian syndrome (PCOS), this paper discusses the clinical curative effect, so as to its functional mechanism for TCM treatment PCOS more effective method. Methods: 60 examples of kidney empty stomach type childbearing age-to PCOS patients randomly divided into two groups: treatment group in 30 cases of the kidney and liver soup oral tone club and the clomiphene citrate (cc); 30 cases in club, oral grams Finn (cc). Observed before and after treatment 3 months to improve the clinical manifestations, menstrual symptoms and the pregnancy, improvement, and serum TCM follicle-stimulating hormone (FSH), luteinizing hormone (LH) and enhanced the ratio