补肾疏肝法治疗肾虚肝郁型多囊卵巢综合征高雄激素血症的临床探究.pdfVIP

提 要 目的：探讨补肾疏肝法治疗肾虚肝郁型多囊卵巢综合征(PCOS)高雄激素血症的 临床疗效及作用机理。方法：将 60 例肾虚肝郁型 PCOS 高雄激素血症患者随机分为 2 组，治疗组 30 例，用补肾疏肝汤；对照组30例，服达英－35。观察治疗前后症状、 体征改善情况，观察血清黄体生成素(LH)、卵泡刺激素(FSH)、泌乳素(PRL)、睾酮(T)、 雌二醇(E ) 、胰岛素(INS)、LH/FSH 的含量变化，观察基础体温（BBT）及 B超的变化。 2 结果：治疗后治疗组和对照组的总有效率分别为90%、66.67%，差异有显著性（P0.05）。 治疗后两组在临床表现、中医症状改善、内分泌指标方面差异有显著性（P0.05）。 结论：补肾疏肝法是治疗 PCOS 高雄激素血症的有效方法之一。补肾疏肝汤可以降低 T、INS 水平，治疗高雄激素血症；通过降低 LH 、LH/FSH 比值改善下丘脑-垂体-卵 巢轴的功能，改善月经，促进排卵。 关键词 补肾疏肝法；多囊卵巢综合征高雄激素血症；肾虚肝郁型；临床研究 Clinical Study on Treatment of the kidney deficiency and liver depression of Polycystic Ovarian Syndrome With Hyper insulinemia with Bu shen Shu Gan Method Speciality: Gynecology of TCM Author: Shi Yange Tutor: Professor Sang Haili Abstract Objective: To observe the effect of Bu Shen Shu Gan Decoction (BSSGD) in treating Polycystic Ovarian Syndrome(PCOS) with Hyper insulinemia with kidney deficiency and liver depression and to explore its mechanism.Methods ：60 patients were divided into two groups at random ：the treatment group(30 cases, treated with BSSGD ) and the control group(30 cases, treated with Dine-35 Tablets). Observe the changes of clinical symptoms and signs, serum hormones(FSH、LH 、T、E 、LH/FSH 、PRL 、INS) levels ，basic body 2 temperature （BBT ）and those of ultrasonic examination. Results: The totle effective rate of the treatment group was 90%, while that of the control group was 66.67%. The difference between the two groups was significant (P0.05). There is significant difference between symptoms, signs and serum hormones levels.Conclusions: BSSGD is an effective recipe in treating of the kidney deficiency and liver depression of Polycystic Ovarian Syndrome(PCOS) with hyper insulinemia. It can regulate the balance of