年轻患者伴大量砂砾体钙化的乳腺黏液癌临床病理观察.pdfVIP

• 214 • J Diag Pathol ,June 2008 ,Vo1. 15 ,No.3 年轻患者伴大量砂砾体钙化的乳腺素占液癌 临床病理观察 刘芳芳，鲍冬梅，阙 秀，沈丹华 (北京大学人民医院病理科，北京 川剧的 [摘要] 目的 探讨伴有砂砾体钙化的乳腺蒙古液癌的临床病理特点、诊断及意义。方法 通过光镜和免疫组化方 法对 1 倒伴有砂砾体钙化的乳腺蒙古液癌的年轻患者组织标本进行观察。结果 乳腺蒙古液癌细胞形态及组织结构 单一，小团肿瘤细胞漂浮在教液湖中较多砂砾体钙化存在于肿瘤组织及教液区域内，ER 和 PR( + )，句A 和 Syn ( - )。结论 乳腺蒙古液癌少见且多发生于〉ω岁女性，该患者年轻且伴有较多砂砾体钙化十分罕见。伴有较多砂 砾体钙化的乳腺蒙古液癌淋巴结无转移，细胞分化好，提示可能具有较为良好的预后。 [关键词] 乳腺蒙古液癌; 砂砾体钙化; 诊断; 顶后 [中图分类号] R735 [文献标识码] A f 文章编号]I ∞7- 刷刷2∞8)03 -但14- 但 Br四st mucinous carcinoma wi由 abundant 醉ammoma 切地i臼 and calcification in a yωng patient UU Fang-fang , BAO Dong-mei , KAN Xi口 ， et 01. (De阳血nent of Pathology , Peking University People s Hospi时， Beijing HX剧4， Cbina) Abs甜act: Objective To study 由e clinicopathological cbaracteristics , dia伊lOStic significance of bre皿mucinous carcin咽la with 严anunoma bodies and calcification. Methods A case of breast mucinous c咀rclnoma wl由严anunoma bodies and calcification was studied by histopathological oh珩凹ation and immunohistochemical staining. Results The histo阳出。，logical feature of the bre剧 mucinous carcinoma was uniform. Clusters of carcinoma cells were fl回ting in the mucus lakes. Tumor tissu白面对 mucus l必esω幽ined many pammoma bodies. Immunobistochemical staining sbowed 阻， PR we陀阳siti回 and CgA, Syn 阴阳 negtive. COnCJUSiOn 四e breast mucinous carcinoma is an i曲呵uent breast cancer and often occurs overωy咽TS. y，侃ng patient wi由 many 萨anunonJa bodies 缸Id calcification is very rare and nJaY has a mo陀 favorable prognosis than usual mucinous carclnoma. Key WOnIS: Bre础t mucinous carcinonJa; PsanJmonJa如dies and calcification; Dia伊曲is; Prognosis 的砂砾体钙化，位于瘤组织或蒙古液湖中(图 1- 3) 。 1 I临床资料 2.2 免疫组化 ER(90% ，附)