Cooperativity Scale_ A Structure–Mechanism Correlation in the Self-Assembly of Benzene-1,3,5-tricarboxamides.pdfVIP

This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License, which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes. Article pubs.acs.org/accounts Cooperativity Scale: A Structure−Mechanism Correlation in the Self-Assembly of Benzene-1,3,5-tricarboxamides Chidambar Kulkarni, E. W. Meijer,* and Anja R. A. Palmans* Laboratory of Macromolecular and Organic Chemistry and Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands S *Supporting Information CONSPECTUS: The self-assembly of small and well-defined molecules using noncovalent interactions to generate various nano- and microarchitectures has been extensively studied. Among various architectures, one-dimensional (1-D) nano-objects have garnered significant attention. It has become increasingly evident that a cooperative or nucleation−elongation mechanism of polymerization leads to highly ordered 1-D supramolecular polymers, analogous to shape-persistent biopolymers such as actin. With this in mind, achieving cooperativity in self-assembled structures has been actively pursued with significant success. Only recently, researchers are focusing on the origin of the mechanism at the molecular level in different synthetic systems. Taking a step