微生态制剂对危重病患者胃肠功能障碍的治疗作用.pdfVIP

生．垒旦筮 鱼鲞筮垒翅 』Clin Sutg。June 2008，Vo1．16．No．6 · 论著 · 微生态制剂对危重病患者胃肠功能障碍的 治疗作用 魏炜 [摘要】 目的 研究微生态制剂(金双歧)对危重病患者胃肠功能障碍恢复的治疗作用及多 器官功能障碍综合征(MODS)的防治。方法 96例ICU胃肠功能障碍的危重病患者，分为两组：金 双歧治疗组(56例)，对照组(4JD例)，观察两组患者胃肠功能评分、Marshall评分、APACHE II评分、 MODS的发生率与病死率。结果 金双歧治疗组治疗后胃肠功能评分、APACHE II评分及Marshall 评分均有所降低，MODS的发生率和病死率均与对照组差异有统计学意义(P0．01)。结论 微生 态制剂对危重病患者胃肠功能障碍具有较好的治疗作用，可明显降低MODS的发生率和病死率。 [关键词】 胃肠功能障碍； 微生态制剂； 多器官功能障碍综合征 [中圈分类号】11573 [文献标识码】A [文章编号]1005-6483(2008)06-0406-03 IlfllflUelll~~of microecologiao modular on the severity of gastrointestinal dysfunction in with multipleorgan dysfunction syndrome WEI (Department ofGeneral Sur- gery，Wuhan Xinzhou Hospital，Hubei 430400，China) [Abstract] Objective To observe the clinical effect of microecologino modular on the gas． trointestinal dysfunction in patients with multiple organ dysfunction syndrome(MODS)．Method Nine． ty—six patients with critical illness，who were admitted to ICU，were divided into 2 groups：the group trea- ted with mieroecdogiao modular(n=56)and the control group(n=40)．The alleviative rate and time of gastrointeminal dysfunction，morbidity and mortality of MODS in 2 groups were observed．Results After treatments，the intestinal dysfunction score，AP ACHEII score and MarshaII score of all patients were de— creased，at the sametime，the therapeutic effects in microecologiao modular group were more significant than in control group(P0．05 or P0．O1)．Conclusion Microecologiao modular might achieve bet． ter effecta on gastrointestinal dysfunction in patients with critical illness，and reduce the morbidity and moro tality of MOI)S obviously． [Key words] gastrointestinal disorder； microecol ao modular； multiple~rgan dysfunc． tion syndrome 本研究旨在探讨微生态制剂对危重患者胃肠功能 一 l9分，平均(7．86±3．74)分；胃肠功能评分