10呼衰（10 failure）.docVIP

10呼衰（10 failure） Iv. Qa: 1. What is the reason that one side of the pulmonary lobe and one side of the lobectomy are more likely to cause respiratory failure? [the] side lobes not easy cause respiratory failure, because of the side lobes not but there is no ventilation flow, the mixed venous blood oxygen partial pressure and oxygen saturation is reduced, leading to hypoxia; On the other hand, the patients with lobectomy only reduced the area of alveolar capillaries, and the blood oxygen partial pressure and oxygen saturation were normal. 2. Test the pathogenesis of pulmonary heart disease. [answer] chronic respiratory failure causes the right hypertrophy and failure as pulmonary heart disease. The pathogenesis is as follows: Alveolar hypoxia and carbon dioxide retention caused by acidosis caused the pulmonary arterial constriction, increasing the right posterior load. (2) pulmonary arteriole long-term shrinkage can cause pulmonary vascular smooth muscle cells and fibroblasts hypertrophy and hyperplasia, elastin and collagen synthesis increase in pulmonary vascular wall thickening and hardening, lumen narrowing to form stable pulmonary hypertension; The chronic hypoxia induced compensatory erythropoiosis may increase the viscosity of the blood and increase the right load. The pulmonary lesion causes the pulmonary capillaries to be destroyed, such as arteritis, pulmonary embolism, and pulmonary hypertension. Hypoxia and acidosis can also reduce the myocardial constriction or diastolic function; When breathing is difficult, inhaling or exhaling can cause abnormal pressure in the chest, which can affect the systolic or diastolic function of the heart. 3. Try to describe the pathogenesis of pulmonary encephalopathy. The pathogenesis of cerebral dysfunction caused by respiratory failure is called pulmonary encephalopathy. The pathogenesis is as follows: The effect of acidosis and hypoxia on cerebral blood vessels Cerebral blood vessels dilation, cerebral blood flow increa