多肿瘤标志物蛋白芯片检测系统在临床应用中的评价(The evaluation of multi-tumor marker protein chip detection system in clinical application).docVIP
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多肿瘤标志物蛋白芯片检测系统在临床应用中的评价(The evaluation of multi-tumor marker protein chip detection system in clinical application)
多肿瘤标志物蛋白芯片检测系统在临床应用中的评价(The evaluation of multi-tumor marker protein chip detection system in clinical application)
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The evaluation of multi-tumor marker protein chip detection system in clinical application
Li xinhe 1
Tannins ning 1
2, the young one
Ase wang 1
Yan-hong liu 1
1 Xia Hong seal
Zou Xiong 1
Clad 2
1. Laboratory of the laboratory of the Zulu hospital of shandong university
jinan
250012
Blood department of Zulu hospital, shandong university
jinan
250012
[abstract] objective: to evaluate the application of multi-tumor marker protein chip in the screening of healthy population, early diagnosis of tumor and the monitoring of prognosis
Methods: 8330 patients with malignant tumor were analyzed by using the hd-2oo1a multi-tumor marker protein chip detection system (c-12)
Of 9657 patients with benign disease and 23531 health checker serum 12 common tumor markers (CA199
NSE
The CEA
CA242
CA125
CA153
AFP
FER
F - PSA
PSA
Levels of beta-hcg and HGH
In the meantime, the E170 automatic immunoassay was performed for 153 negative specimens of malignant tumor group
Results: the positive rate of malignant tumor group (85.6%) is significantly higher than benign disease group (41.2%) and health TiJianZu (7.03%) (P 0.05),
C-12 has a 95 percent specificity for healthy population detection
The detection rate for healthy people was 0.2%
Conclusion: multi-tumor marker protein chip detection technology has high sensitivity and specificity
Using protein chip technology to detect multiple tumor markers can significantly improve the sensitivity of malignant tumor diagnosis
It can be used to observe the prognosis and curative effect
It can also be used as an early screening tool for asymptomatic populations
The census of high-risk groups has some guiding significance
Keywords: tumor markers; Protein chips; Chemiluminescence analysis
The Evaluation of Clinical Application of Detective System of multi-tumor Markers P
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