膝交叉韧带中机械感受器的研究进展.pdfVIP

. 930 . 中国骨与关节杂志 2016 年 12 月第 5 卷第 12 期 Chinese Journal of Bone and Joint, December 2016, Vol 5, No.12 . 综述 Review . 膝交叉韧带中机械感受器的研究进展 党保平　闫金洪　韩一生 DOI: 10.3969/j.issn.2095-252X.2016.12.011　　中图分类号：R684.3 作者单位：710032 西安，第四军医大学西京医院骨科 通信作者：韩一生，Email: drhanys@ Progress in studies on the mechanoreceptors in the cruciate ligament DANG Bao-ping, YAN Jin-hong, HAN Yi-sheng. Department of Orthopaedics, Xijing Hospital, the fourth Military Medical University, X’ian, Shanxi, 710032, PRC Coponding author: HAN Yi-sheng, Email: drhanys@ Abstract Cruciate ligament of the knee lies between tibia intercondylar eminence and femoral condyle 【 】 nest, presents hinged appearance and has both the function of biomechanics and proprioception, which is processed using mechanoreceptors in the tibial and femoral ligament attachment point. Mechanoreceptors could be divided into 4 groups: Ruffini ending, Pacinian body, Golgi tendon ending, and free nerve ending. The amount of mechanoreceptors of the cruciate ligament after acute injury will change in line with the duration of injury: the longer the time lasts, the less the receptors will be. But some hold the opposite view and consider that the receptors do not have evident atrophy and decline. Due to inflammation in the progression of osteoarthritis, cruciate ligament will gradually degenerate, and knee proprioception will abate as well. However, whether the amount of mechanoreceptors are associated with osteoarthritis progression and severity of the situation is not clear. The number of the damaged cruciate ligament mechanoreceptors and proprioception can recover partly after transplantation and repair, but not fully recover. Therefore, whether separated and cultured cells in vitro can be used in tissue engineering for ligament transplantation and repair, and improve proprioception, is what we need to pa