中西医结合治疗封闭抗体不足性反复流产46例临床观察.docVIP

中西医结合治疗封闭抗体不足性反复流产46例临床观察【摘 要】 目的:探讨中西医结合治疗封闭抗体不足性反复流产的临床疗效。方法：选择确诊患者86例，随机分为西医治疗对照组40例，中西医结合治疗组46例。对照组采用丈夫淋巴细胞免疫治疗，治疗组采用加味玉屏风散联合丈夫淋巴细胞免疫治疗，免疫治疗3周注射一次，4次为一个疗程，观察2个周期，并观察其妊娠结局。结果：86例均完成了治疗，对照组在免疫治疗一个疗程后，封闭抗体全部转阳有11例，第二疗程有21例；治疗组在第一个疗程后转阳24例，第二疗程有20例。对照组共有30例成功妊娠，治疗组共有42例成功妊娠。治疗组在BA的转阳速度、转阳率和成功妊娠率上都优于对照组，差异有统计学意义（P0.05）。结论：中西医结合治疗封闭抗体不足性反复流产疗效肯定，但其具体的作用机制仍有待于进一步深入研究。 【关键词】 中西医结合； 封闭抗体； 反复流产； 免疫治疗 Integrated western and Chinese therapy on recurrent spontaneous abortion caused by blocking antibody deficiency ZHOU Aixiang Department of Obstetrics and Gynaecology, Ma Anshan Municipal Hospital of Women and Children’s Health, Anhui 243000, China 【Abstract】 Objectives: To explore the effect of Integrated western and Chinese therapy on recurrent spontaneous abortion caused by blocking antibody deficiency. Methods: Eighty-six patients were selected and randomly divided into the treatment group(46 cases) and the control group(40 cases). The control group was treated with the spouse?s lymphocyte immunotherapy. The treatment group was treated with supplement Yupinfengsan combined with lymphocyte immunotherapy. Immunotherapy was administered once every 3 weeks and 4 times as a treatment course. The therapeutic effects were observed after two treatment courses. Results: Among 86 patients who finished the treatments, 11 of the control group showed positive blocking antibody after one treatment course, 21 showing positive after two treatment courses; 24 of the treatment group indicated positive antibody after one course, 20 cases revealing positive after two courses. The control group produced 30 cases of successful pregnancy, and the treatment group producing 42 cases. The treatment group showed significant advantage over the control group in BA positive-transforming speed, rate and in pregnancy success rate (P0.05). Conclusion: Integrated western and Chinese therapy proves to be effective in treating recurrent spontaneous abortion caused by blocking antibody de