中西医结合治疗围绝经期综合征患者临床疗效观察.doc

中西医结合治疗围绝经期综合征患者临床疗效观察[摘要] 目的：研究中西医结合治疗围绝经期综合征患者前后甲襞微循环、雌激素及血脂变化。方法：对60例正常妇女（CON）、60例无症状围绝经期妇女（PM）、60例围绝经期综合征妇女（PMS）在治疗前检测甲襞微循环、雌激素及血脂，并进行组间比较；另外对PMS妇女在中西结合治疗后进行甲襞微循环、雌激素及血脂检测，并与治疗前对比观察。结果：PM组和PMS组分别与CON组甲襞微循环、雌激素及血脂比较，差异有非常显著性(P＜0.01)；PM组和PMS组甲襞微循环、雌激素及血脂比较，无统计学意义（P0.05）；PMS组中西药结合治疗前后甲襞微循环、雌激素及血脂比较，差异有非常显著性(P＜0.01)。结论：中西医结合治疗围绝经期综合征，可使甲襞微循环、雌激素及血脂指标有显著的改善，疗效肯定。 [关键词] 围绝经期综合征；中西医结合治疗；甲襞微循环；雌激素；血脂 [中图分类号]R711 [文献标识码]B [文章编号]1673-7210（2007）08（c）-086-03 Clinical study on treatment of the patients with perimenopausal syndrome with the conbined treatment of traditional Chinese medicine and Western medicine HAN Yue,XIE Hui-lian,ZHANG Zi-ling,ZHAO You-fen,XIA Xue-min (The second People’Hospital of Guiyang,Guiyang 550005,China) [Abstract] Objective:To explore the change of nail fold microcirculation,female hormone and blood lipid on the patients with perimenopause syndrome before and after the conbined treatment of traditional Chinese medicine and Western medicine.Methods:The several data of nail fold microcirculation,female hormone and blood lipid were obtained and compared among three groups before treatment. The three groups were Group Control,Group PM (women in perimenopausal period) and Group PMS(patients with perimenopausal syndrome),60 samples in each group.And the above data were compared in Group PMS before and after treatment. Results:There was significant difference of nail fold microcirculation,female hormone and blood lipid among Group Control,Group PM and Group PMS before treatment of traditional Chinese medicine and Western medicine (P0.05),but was significant in Group PMS before and after treatment (P 1.2.3 统计学方法 采用t检验。 2 结果 治疗结果见表1～6。 由表1可见，治疗前PM组和PMS组分别同CON组比较，各积分值明显升高，经统计学处理，差异有非常显著性(P＜0.01)；PM组与PMS组比较无统计学意义(P0.05)。PM组和PMS组甲襞微循环表现在管襻畸形、扭曲、输入支和输出支血管痉挛、血流变慢、血液黏度增高、管襻周围水肿、出血、乳头下静脉丛扩张、汗腺导管＞3条以上、可见汗滴。 由表2可见，PMS组治疗后与治疗前比较，差异有非常显著性（P＜0.01）。PMS组患者经中西医结合治疗3个疗程后，血管输入输出支痉挛得到缓解，血管扩张，血流速度加快，襻周水肿、出血消失，汗腺导管减少等，甲襞微循环的加权积分值下降。 由