橘核丸治疗少、弱精子症及男性不育病因探究.docVIP

橘核丸治疗少、弱精子症及男性不育病因探究[摘要] 目的:探讨男性不育的可能病因及构成情况,为临床治疗提供更多科学依据和选择。方法:总结52例不育患者的一般资料。在精液常规分析的基础上,进一步合理选择精浆生化检测、血清性激素检测、生殖道感染的检测与睾丸活检等检查。结果:附性腺慢性感染28例,占53.84%;继发性不育症36例,占69.23%。其中,附性腺感染率和继发性不育症感染率较往年增加。前列腺炎、附睾炎、睾丸炎的发病率也较数年前显著增加。结论:本研究为临床分析和治疗男性不育提供了参考。 [关键词] 男性不育;实验室检查;病因分析 [中图分类号]R256.56 [文献标识码] B[文章编号] 1673-7210(2009)08(a)-195-03 Treatment of less asthenospermia with Seminis Citri Reticulatae Pills and analysis of the causes of male infertility CHENG Kejia (Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China) [Abstract] Objective: To investigate the possible causes and composition of male infertility, and provide more reliable basis and choices for clinical treatment. Methods: Data of 52 cases of infertility patients were analyzed. Besides the conventional analysis of semen, seminal biochemical detection, serum sex hormones, reproductive tract infections detection, and testicular biopsy were selected for further examination. Results: 28 cases were attached gonad chronic infection, accounting for 53.84%, 36 cases were secondary infertility patients, accounting for 69.23%. Among them, the infection rate of attached gonad and secondary infertility was increased compared with that of previous years. The incidences of prostatitis, epididymitis and orchitis also increased significantly. Conclusion: Our study provides a reference for the clinical analysis and treatment of male infertility. [Key words] Male infertility; Laboratory tests; Etiology analysis 在观察橘核丸对少、弱精子症患者精子质量及生精细胞凋亡的影响的同时,了解男性不育的病因、构成情况及橘核丸对少、弱精子症患者精子质量影响和疗效探讨。在中医药治疗育龄男性少精、弱精症的临床新药、新途径方面作出有益的探索。现将笔者2006年2月～2007年1月收集的52例患者分析并报道如下: 1 资料与方法 1.1 一般资料 52例患者均为我院2006年2月～2007年1月中医男科门诊患者,年龄25~39岁,平均(28.0±4.1)岁;婚龄2~12年,平均(6.0±3.2)年。男性不育症诊断标准:育龄男性与女方同居1年以上,有正常性生活,未采取任何避孕措施,女方生殖功能正常而不能受孕,其精液常规(连续3次均值)有2项或2项以上指标异常。 1.2 各项检查 病史采集、体格检查、睾丸大小测量采用卡尺测量法。精液常规检查:按照WHO精液检查标准检测精液量、黏稠度、液化时间、精子密度、精子活力、精子存活率、精子形态学分析等项目[1]。对所有患者精液和(或)前列腺按摩液(EPS)进行细菌、微生物学检查。19例疑为梗阻性无精子症的患者做B超检查及活检。5