老年人住院用药现状及其相关因素研究.docVIP

老年人住院用药现状及其相关因素研究【摘要】目的：分析老年住院病人用药现状及相关因素，指导合理用药。方法：采用人群随机抽样研究方法对我院2006年1月～2006年10月收治住院的老年病人用药情况及其相关因素进行统计分析。结果：本组抽样获得的213例病人中，大多老年住院病人有两种或两种以上疾病，有2/3病人同时使用7种或7种以上药物治疗，其中同时使用≥10种者高达34.74%。老年住院病人使用药物数量与其所患疾病种类数、住院时间有明显相关性(P＜0.05）。本组资料老年住院病人药物相关的不良反应发生率为7.98%，主要为胃肠道反应、皮疹、出血凝血时间延长及心血管系统等。结论：老年人所患疾病多、住院时间过长是造成用药种类多的重要因素，亦是极易发生药物相互作用和不良反应的主要原因。 【关键词】老年人；药物不良反应；住院时间 文章编号：1009-5519（2007）11-1601-02 中图分类号：R9 文献标识码：A Current situation of medication and analysis of their correlation factors in the aged in-patients TAN Guang-jun，ZHOU Xun-ping，DU Fang （Department of geriatrics，The First Affiliated Hospital of Chongqing Medical University，Chongqing 400016，China） 【Abstract】Objective：To analyze the current situation of medication and analysis of their correlation factors in the aged in-patients in order to guide rational administration. Methods:The current situation of medication and correlation factors in the aged in-patients admitted to this hospital from January 2006 to October 2006 were analyzed by random sampling of population.Results:Of 213 elderly in-patients acquired by random sampling，a major of them suffered from two or more than two kinds of diseases，two-thirds of them were administered seven or more than seven kinds of drugs at the same time， more than ten kinds of agents accounted for 34.7%. There was obvious correlation between drug numbers administered to the aged in-patients and number of diseases or length of stay of them(P0.05). The incidence rate of drug adverse reaction in these patients was 7.89%，predominantly including gastrointestinal tract reaction，rash，prolonged time of bleeding and coagulation，cardiovascular system and so on.Conclusion:The much more kinds of diseases and long hospital time stay were the important factors to cause medication of the aged in-patients too more and the main causes that lead to occurrence ofdrug interactions and adverse effects. 【Key words】The aged；Drug side effect；Length of stay 本文采用随机抽样法对我院2006年1～10月收治住