注意缺陷多动障碍儿童眼动抑制缺陷对照探究.docVIP

注意缺陷多动障碍儿童眼动抑制缺陷对照探究【摘 要】目的:探讨注意缺陷多动障碍(Attention Deficit Hyperactivity Disorder,ADHD)儿童在抑制性眼动任务中的反应特征。 方法:采用注视、主动眼动及反向眼动任务对21例ADHD儿童和21例正常对照儿童进行评估。 结果:(1)注视任务中,ADHD组侵入性眼跳数目高于对照组[无分心条件:(12.67±12.28) vs.(6.38±6.95),P=0.040;分心条件:(16.91±10.00) vs.(11.29±5.99),P=0.030];(2)主动眼动任务中,两组儿童眼跳参数差异无统计学意义;(3)反向眼动任务中,ADHD组眼跳方向错误率高于对照组[间隔条件:(68.14±17.85) % vs.(54.10±20.22) %,P=0.020;重叠条件:(62.49±17.54) % vs.(49.27±17.21) %, P=0.020]。 结论:注意缺陷多动障碍儿童眼动抑制能力存在缺陷,推测可能是由于注意缺陷多动障碍儿童具有异常的额叶-纹状体结构和/或功能所致。 【关键词】注意缺陷多动障碍;眼动任务;抑制;眼跳; 病例对照研究 中图分类号:R749.94 文献标识码:A 文章编号:1000-6729(2010)001-0038-05 doi:10.3969/j.issn.1000-6729.2010.01.009 Inhibitory deficits of oculomotor behavior in children with attention deficit hyperactivity disorder CHEN Qiang1,2,JING Jin1,YANG Wen-Han?1 ?1Department of Maternal and Child Health,School of Public Health,Sun Yat-sen University, Guangzhou 510080,China ?2Department of Child Psychological Behavior,Zhuhai Maternal and Child Health’s Hospital, Zhuhai 519000,Guangdong Province,China Corresponding author:JING Jin,E-mail:jingjin@mail.sysu.省略 【Abstract】Objective:To examine the characteristics of oculomotor inhibition about children with attention deficit hyperactivity disorder(ADHD).Methods:Twenty-one children with ADHD according to the Diagnostic and Statistical Manual of Mental Disorder,4th edition(DSM-IV) and 21 matched controls were administered with fixation,prosaccade and antisaccade tasks.Results:(1) In the fixation task,the children with ADHD demonstrated significantly more intrusive saccade errors than the controls in either condition with distractors or without distractors[no distractors:(12.67±12.28) vs.(6.38±6.95),P=0.040;distractors:(16.91±10.00) vs.(11.29±5.99),P=0.030].(2) In the prosaccade task,there were no significant differences found between groups in saccadic parameters,in either gap condition or overlap condition.(3) In antisaccade task,the direction error rates of the ADHD group in either gap condition or overlap cond