贵州小型猪消化道嗜银细胞的年龄变化观察-第三军医大学学报.DOC

老龄贵州小型猪消化道嗜银细胞的分布及形态学观察 赵海1 钱宁1刘霞2 詹新义1 吴曙光* [摘要] 目的 探讨消化道嗜银细胞的分布、密度及形态。方法 采用改良的Pascual双重银染老龄贵州小型猪食道、胃、十二指肠、空肠、回肠、盲肠、结肠、直肠黏膜嗜银细胞分布和形态，并分析老龄和青年贵州小型猪消化道嗜银细胞。结果 老龄除食道外各部位均有嗜银细胞，胃体布密度最高，胃门部最低嗜银细胞形态和分布猪相似；嗜银细胞形态多样，主要有椭圆形、锥体形圆形以及，广泛分布于腺泡上皮细胞之间上皮细胞之间0.01)。 结论 老龄贵州小型猪消化道嗜银细胞数量少，其消化道内分泌功能减退。根据结构形态可以消化道内嗜银细胞具内外2种分泌功能 [关键词] 贵州小型猪；嗜银细胞；消化道；老龄 Distribution and morphology observation of argyrophilic cells in digestive tract of aging guizhou miniature pig Zhao Hai1，，，，* （, 2. Basic medical, Guiyang College of Traditional Chinese Medicine, Guiyang Guizhou, 550002） ’ methods and image analysis, and then, to explore the change in the number of argyrophilic cells through comparative analysis between aging and youth of guizhou miniature pig. Results The results showed that there were no argyrophilic cells in esophagus, but distributing widely in the other place of digestive tract of aging guizhou?miniature?pig. The distribution density of argyrophilic cells was highest in the body of stomach, followed by gastric antrum, which was lowest in colon. The morphology and distribution of argyrophilic cells in digestive tract were similar to young pigs; The shapes of argyrophil cells were diverse, there was ellipse, tapering, round and shuttle, The argyrophil cells distribute at between glandular epithelial cells, mucosal epithelial cells and basal region of it; To compare the distribution density of argyrophilic cells in digestive tract between aging and youth guizhou miniature pigs, the secretory granules and quantity of argyrophilic cells were reduced, besides the ileum, other parts of digestive tract have extremely significant difference (P0.01). Conclusion The number of argyrophilic cells in digestive tract of aging guizhou miniature pig less than youth pigs, which endocrine function was reduced. According to the distribution density and morphology of argyrophilic cell in the digestive tract of guizhou?miniature?pig, the argyrophilic cell might might have more than two kinds of secretio