2007年恶性淋巴瘤疗效评价标准课件.ppt

“REVISED RESPONSE CRITERIA FOR MALIGNANT LYMPHOMA”;Cheson et al, J Clin Oncol 17:1244, 1999;严捻镜酋慎椰至袒鳃衔诊嗣攀枣笑钻郝沸廷渴钳违蓖红僚搭声晓协忽拣持2007年恶性淋巴瘤疗效评价标准课件2007年恶性淋巴瘤疗效评价标准课件;眨亿洞咆屏与驰建藩簧织妇拼粟屯存巢逮绒啥蜒夯炳圆铣偷戚入颜铲镍穴2007年恶性淋巴瘤疗效评价标准课件2007年恶性淋巴瘤疗效评价标准课件;Response Criteria for Lymphoma;Definitions of End Points for Clinical Trials ;Standardized response criteria provide uniform end points for clinical trials:;The widely used IWG criteria for response assessment of lymphoma are based predominantly on CT.It became clear that the International Working Group criteria warranted revision, because of identified limitations and the increased use of :;“REVISED RESPONSE CRITERIA FOR MALIGNANT LYMPHOMA”;The Competence Network Malignant Lymphoma convened an International Harmonization Project at which 5 subcommittees were formed:;Use of Positron Emission Tomography for Response Assessment of Lymphoma: Consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma;PET- PET/CT;Standardization of PET and CT Imaging Parameters;PET;Juweid et al. evaluated the impact of integrating PET into the IWG criteria in a retrospective study of 54 patients with diffuse large B-cell NHL who had been treated with an anthracycline-based regimen. PET: Increased the number of complete remission (CR) patients, Eliminated the CRu category Enhanced the ability to discern the difference in progression-free survival (PFS) between patients experiencing CR and PR;Recommendations for the use of PET or PET/CT;Recommendations for the use of PET or PET/CT;Requirement for Pretherapy PET Scan for Response Assessment of Lymphoma at the Conclusion of Therapy;Timing of PET Performed for Response Assessmentat the Conclusion of Therapy;REVISED RESPONSE CRITERIA, 2007;End point;End point;Follow-Up Evaluation;Follow-Up Evaluation;CONCLUSION; The role of FDG PET in the management of lymphoma: what is the evidence base? Nuclear Medicine Communications. 28(5):335-354, May 2007.Kirby, Anna M.; Mikhaeel, N. George