第十二章 细胞分化与基因表达调控（The twelfth chapter of cell differentiation and gene expression regulation）.docVIP

第十二章 细胞分化与基因表达调控（The twelfth chapter of cell differentiation and gene expression regulation） The twelfth chapter is the regulation of cell differentiation and gene expression Teaching objectives: 1.. Understand the concept and regulation mechanism of cell differentiation, master the basic concepts of housekeeping genes, luxury genes, cell totipotent and stem cells. 2. understand the molecular mechanisms of cell carcinogenesis and the basic features of cancer cells. 3. to understand the regulatory mechanism of eukaryotic gene expression at the transcriptional level, post transcriptional level and translation level. Two. Teaching emphasis: 1. the essence and influencing factors of cell differentiation; the molecular mechanism of 2 cell carcinogenesis and the basic characteristics of cancer cells. Three. Teaching difficulties: transcriptional level of gene regulation. Four. Teaching methods and teaching methods: teaching, discussion, multimedia assisted instruction. Four. Teaching content: In the process of individual normal development, and increase the cell number by controlled cell division, and increase the cell types by cell differentiation and orderly, and by different types of cells of the tissues and organs of the organism, perform different functions. Obviously, cells differentiate into some kind of cell groups, and complete a variety of complex and special biological functions through mutual coordination, which lays the foundation for the development and evolution of life at a higher level. Cell differentiation (cell differentiation): in the individual development, by the same kind of cell types by cell division gradually in morphology, structure and function of the formation of stability differences, produced in the process of the different cell groups. Its essence lies in the differential expression of tissue-specific genes in time and space Cell differentiation is the basis and core of multicellular organism development; The key to cell differentiation is