02病因学（02 etiology）.docVIP

02病因学（02 etiology） The second chapter is etiology The periodontal disease initiation factor - plaque ? local irritation of periodontal disease The systemic predisposing factors of periodontal disease The periodontal disease initiation factor - plaque The first section of periodontal disease initiation factor - plaque Plaque biofilm Characteristic: it is an organism with definite structure, in which the bacteria can resist the function of hosts defense, surface active agent or antibiotic, and it is not easy to be washed away by water Two. Subgingival plaque and subgingival plaque Plaque; contact tissue; predominant bacteria; influencing factors; pathogenicity Subgingival plaque: enamel, gingival margin, exposed cementum, gram positive aerobic bacteria Facultative bacteria, oral hygiene, measures Food mechanical friction Saliva caries Gingivitis Tartar Adhesive subgingival plaque: root cementum in periodontal pocket; Gram-positive Gram-positive bacteria Anaerobic gingival crevicular fluid Sulcus PD physical spatial root caries periodontitis Subgingival calculus Non adherent subgingival plaque: gingival sulcus epithelium, junctional epithelium, pocket epithelium, anaerobic bacteria, ditto periodontitis Three. Plaque microorganisms as evidence of periodontal disease initiating factor (I) epidemiological investigation; The distribution, prevalence and severity of periodontal disease are positively related to oral hygiene and plaque accumulation (two) experimental gingivitis was observed 1965 Loe reports: 12 periodontal health dental students Discontinuation of oral hygiene measures 1-3 weeks caused gingivitis Gingival health was restored 1 weeks after dental rehabilitation (three) animal experimental study 1. experimental periodontal inflammation Dental calculus or ligation + bacteria of periodontal inflammation Dental calculus or ligation and sterile animal without gingival inflammation 2., the transmission of periodontitis (four) host immune response Increase in antibo