慢性移植物抗宿主病的研究与进展.pdfVIP

中国组织工程研究与l临床康复 第J2眷 3 2008一Ol一15出版 Journal ofClinical Rehabilitative Tissue Engineering Research January 15，2008 Vo1．12，No．3 慢性移植物抗宿主病的研究与进展☆ 周 虹，赵春华 $女 { … 罐 嗨 § 籍 稚 ≈ Research progress in chronic graft versus host disease Zhou Hong，Zhao Chun—hua Abstract BACKGR0UND：The mature a B T cells exist in allograft cannot only rebuilt the immunologic ability of T cells in the recipient center of Tissue body but also cleanse the malignant cells as wel1．However。those T cells recognizing recipient as”non—self’at the same time can Engineering， Peking Union Medical attach the body via immunologic mechanism on a large scale．or graft verse host disease in genera1． College ＆ Chinese OBJECTIVE：To summarize the recent progression of chronic graft versus host disease． Academy of Medical RETRm VAL STRATEGY：A cornputer based search was conducted in Pubmed database for literatures published from January science． Beijing 1OO0o5．China 2O0o to September 20o7 witl1 the key words of”HSCT，chronic GVHD，immunologic suppression”in English．The data were primarily checked，and quotations of each article were checked out．Inclusive criteria included(Dbasic research and clinical Zhou ltong ☆ ． treatment of chronic graft versus host disease，( on the same circle，articles recently published or in authoritative iournals． Studying for Exclusive criteria included repetitive research．A total of 65 literatures were selected and 40 articles met the inclusive criteri色Th e doctorate，Center of Tissue Engineering， excluded 25 articles were with old content or repetitive