characterization of sucrose thin films for biomedical applications蔗糖薄膜的表征生物医学应用.pdfVIP

Hindawi Publishing Corporation Journal of Nanomaterials Volume 2011, Article ID 291512, 6 pages doi:10.1155/2011/291512 Research Article Characterization of Sucrose Thin Films for Biomedical Applications S. L. Iconaru,1 F. Ungureanu,1 A. Costescu,1 M. Costache,2 A. Dinischiotu,2 and D. Predoi1 1 Department of Multifunctional Nanoparticles for Biomedical Applications, National Institute of Materials Physics, P.O. Box MG7, Magurele, 077125 Bucharest, Romania 2 Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania Correspondence should be addressed to D. Predoi, dpredoi@ Received 29 July 2010; Accepted 8 February 2011 Academic Editor: Kui Yu Copyright © 2011 S. L. Iconaru et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Sucrose is a natural osmolyte accumulated in the cells of organisms as they adapt to environmental stress. In vitro sucrose increases protein stability and forces partially unfolded structures to refold. Thin films of sucrose (C12H22 O11) were deposited on thin cut glass substrates by the thermal evaporation technique (P ∼ 10−5 torr). Characteristics of thin films were put into evidence by Fourier Transform Infrared Spectroscopy (FTIR), X-ray Photoelectron Spectroscopy (XPS), scanning electron microscopy (SEM), and differential thermal analysis and thermal gravimetric analysis (TG/DTA). The experimental results confirm a uniform deposition of an adherent layer. In this paper we present a part of the characteristics of sucrose thin films deposited on glass in medium vacuum conditions, as a part of a culture medium f