association between severity of cannabis dependence and depression大麻依赖和抑郁的严重程度之间的联系.pdfVIP

Psychology, 2010, 1, 233-237 233 doi:10.4236/psych.2010.14031 Published Online October 2010 (http://www.SciRP.org/journal/psych) Association between Severity of Cannabis Dependence and Depression Karina Karolina Kedzior1,2*, Mathew Martin-Iverson1,2 1,2Clinical Neurophysiology Unit, Graylands Hospital, Mt Claremont, Australia; 1,2Pharmacology Anaesthesiology Unit, School of Medicine Pharmacology, Faculty of Medicine, Dentistry Health Sciences, University of Western Australia, Crawley, Australia. Email: kkedzior@.au th st rd Received May 19 , 2010; revised June 21 , 2010; accepted August 23 , 2010. ABSTRACT Objective. The aim of the current study was to investigate the relationship between self-reported severity of cannabis dependence and symptoms of depression. Method. The lifetime diagnoses of depression and cannabis misuse (abuse and/or dependence) were obtained from 50 participants recruited from the general community, using a self-completed diagnostic interview (CIDI-Auto 2.1). The lifetime severity of cannabis dependence was established using a standard questionnaire, Severity of Dependence Scale (SDS). Results. Of the 19 participants with mental illness diagnoses, 14 (74%) reported depression symptoms. The 14 participants with depression diagnoses had significantly more cannabis misuse diagnoses and significantly higher SDS scores compared to those without mental illness diagnoses (N = 31). SDS scores significantly predicted presence or absence of CIDI depression diagnoses with a 69% overall rate of cor- rect predictions. As SDS scores increased the odds of classification into depressed versus non-depressed groups was 1.3 (95% C.I. 1.02-1.57). Conclusion. The presence of lifetime depression symptoms is associated with higher lifetime