calcaneal bmd obtained by dual x-ray and laser predicts future hip fractures—a prospective study on 4？398 swedish women跟骨骨密度得到双x光和激光预测未来4日臀部fractures-a前瞻性研究 398瑞典女性.pdfVIP

SAGE-Hindawi Access to Research Journal of Osteoporosis Volume 2010, Article ID 875647, 6 pages doi:10.4061/2010/875647 Research Article Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures—A Prospective Study on 4 398 Swedish Women Torkel B. Brismar,1 Imre Janszky,2 and L. I. M. Toft1, 3, 4 1 Division of Radiology, Department for Clinical Science, Intervention and Technology, Karolinska Institute, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden 2 Division of Public Health Epidemiology, Department for Public Health Sciences, Karolinska Institute, 17177 Stockholm, Sweden 3 Merck Sharp Dohme, 192 78 Sollentuna, Sweden 4 Pfizer AB, Stockholm, 191 90 Sollentuna, Sweden Correspondence should be addressed to Torkel B. Brismar, torkel.brismar@ Received 22 October 2009; Revised 8 March 2010; Accepted 15 March 2010 Academic Editor: Roger Price Copyright © 2010 Torkel B. Brismar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The predictive value of dual X-ray and laser (DXL) calcaneal BMD (BMDDXL ) on hip fractures was prospectively studied in 4,398 females aged 55 to 99 years. The average follow-up period was 3 years and 11 months with a total of 17,270 person years. Fractures were identified from the national patient register. After inclusion, 130 females sustained a hip fracture. The age adjusted hazard ratio for T-score −2.5 versus −2.5 was 2.64. Of all patients who sustained a hip fracture 78% had a T-score of −2.5 or below. The annual hip fracture rate was 0.26% at T-scores ≥ −2, but 1.5% at T-scor