characterization of a murine anti-laminin-1 monoclonal antibody (ak8) produced by immunization with mouse-derived laminin-1特征的小鼠anti-laminin-1单克隆抗体(ak8)由免疫mouse-derived laminin-1.pdfVIP
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characterization of a murine anti-laminin-1 monoclonal antibody (ak8) produced by immunization with mouse-derived laminin-1特征的小鼠anti-laminin-1单克隆抗体(ak8)由免疫mouse-derived laminin-1
Clinical Developmental Immunology, March 2005; 12(1): 67–73
Characterization of a murine anti-laminin-1 monoclonal antibody
(AK8) produced by immunization with mouse-derived laminin-1
1,2 2 2 3
AKANE KONDO , JUNKO INAGAKI , KAZUKO KOBAYASHI , HIDEO TSUKAMOTO ,
DAISUKE YAMAMOTO4 5 6
, MIKIYA NAKATSUKA , NOBUHARU SUZUKI ,
6 7 1
MOTOYOSHI NOMIZU , SATOSHI AMANO , HIDEHIKO MATSUBAYASHI ,
2 8 9 1
TATSUJI YASUDA , LUIS R. LOPEZ , YEHUDA SHOENFELD , TSUNEHISA MAKINO ,
EIJI MATSUURA2
1Department of Obstetrics and Gynecology, Center for Specialized Clinical Science, Tokai University, School of Medicine,
Ishehara, Japan, 2Department of Cell Chemistry, Okayama University Graduate School of Medicine and Dentistry, 2-5-1
Shikata-cho, Okayama 700-8558, Japan, 3Department of Laboratory for Molecular Science Research, Tokai University,
School of Medicine, Ishehara, Japan, 4Biomedical Computation Center, Osaka Medical College, Takatsuki, Japan,
5Department of Obstetrics and Gynecology, Okayama University Hospital, Okayama, Japan, 6Tokyo University of Pharmacy
and Life Science, Hachiouji, Japan, 7Shiseido Life Science Research Center, Yokohama, Japan, 8Corgenix Inc, Westminster,
Colorado, USA, and 9Department of Medicine B and Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer,
Israel
Abstract
Laminin-1 is a structural glycoprotein that forms an integral part of the scaffolding of basement membranes, and plays an
important role during embryonic development. We have recently de
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