盐酸达克罗宁胶浆在胃镜检查中应用研究.docVIP

盐酸达克罗宁胶浆在胃镜检查中应用研究[摘要] 目的 盐酸达克罗宁胶浆在胃镜检查中的应用分析，与2%盐酸地卡因局部喷洒进行对比，评估盐酸达克罗宁胶浆的麻醉润滑效果、祛泡效果以及用药的安全性。方法 选择需要胃镜检查的门诊病人和住院病人400例，随机分成两组:试验组、对照组各200例。检查前10-15分钟试验组口服扬子江药业集团有限公司生产盐酸达克罗宁胶浆10ml，对照组用2%盐酸地卡因于咽喉部作局部粘膜喷洒，有麻木感后，行胃镜检查。结果 试验组在插镜及麻醉效果、祛泡效果及口感明显优于对照组。结论 麻醉、润滑、祛泡作用于一体，效果好且无明显不良反应，操作安全，使用方便，值得推广。 [关键词] 盐酸达克罗宁； 胃镜检查 [中图分类号] R969.4[文献标识码] A[文章编号] 1005-0515（2011）-03-060-01 The Anal0ysis on the Application of Dyclonine Hydrochloride Mucilage in Gastroscopy YANG HuiTIAN Ting (The Second Affiliated Hospital of Guiyang Medical College,556000) [Abstract] Objective To evaluate the anesthesia lubrication effect，remove bubble effect and drug safety of Dyclonine Hydrochloride Mucilage by comparing the analysis on the application of Dyclonine Hydrochloride Mucilage in gastroscope inspection with 2% Tetracaine hydrochloride with for topical spraying. Method To select 400 cases of outpatients and inpatients who are in needof gastroscope inspection,and to divide them into experimental group and control group randomly with 200 cases in each. The experimental group was treated with 10ml Dyclonine Hydrochloride Mucilage made in Yangtze Pharmaceutical Group Co., LTD 10 to15 minutes before the test while the control group using 2% lidocaine hydrochloride for local mucosal spraying in the throat with gastroscope inspection after numbness. Result The experimental group is obviously better than the control group in the aspects of inserted mirror,anaesthetic effect,removing bubble effect and taste. Conclusion The anesthesia, lubrication, remove bubble function together,there will be good effect with no obvious adverse reactions .It will be safe, easy to use, and worth promoting. [Keywords] Dyclonine Hydrochloride Mucilage; Gastroscope inspection. 基层医院由于条件的限制，无痛胃镜尚未开展，有相当一部分病人，惧怕作胃镜检查，部分患者在胃镜检查时躁动、恶心、呕吐，甚至自行拔镜，不仅影响了检查者的操作，容易漏诊、误诊，甚至会造成贲门撕裂等并发症的发生。给病人的诊断和治疗带来一定的影响，甚至延误病情。目前国内许多临床单位采用2％盐酸地卡因或1％盐酸达克罗宁溶液作咽喉部局部喷雾麻醉，辅以口服二甲基硅油祛泡，手续烦琐，无统一剂量。自2009年6月至2010年12月使用盐酸达克罗宁胶浆于200例胃镜检查中取得了良好