社区糖尿病患者糖化血红蛋白影响因素研究.doc

社区糖尿病患者糖化血红蛋白影响因素研究摘 要 目的：了解上海五角场镇社区2型糖尿病患者血糖控制水平，探讨影响糖尿病患者糖化血红蛋白（HbA1c）水平的因素，为糖尿病患者的社区管理提供依据。方法：随机选择确诊的2型糖尿病患者676名，测量身高、体重、血压、腰围、臀围，检测血糖、血脂、HbA1c等。依据HbA1c控制是否达到7.0%为标准，分为A组(7.0%)和B组(≥7.0%)，回顾分析可能影响糖尿病患者糖化血红蛋白水平的因素，采用SAS 9.1.3进行统计学分析。结果：A组中糖化血红蛋白水平受体重指数（BMI）、腰臀比、空腹血糖、葡萄糖耐量试验（OGTT）、高密度脂蛋白（HDL-C）的影响，差异有统计学意义(P0.05)；B组中糖化血红蛋白水平受到空腹血糖和OGTT的影响，差异有统计学意义(P0.05)。结论：糖化血红蛋白可能受到体重指数、腰臀比、空腹血糖、OGTT、和HDL-C的影响。控制饮食、减轻体重、减小腰围及定期检测糖化血红蛋白对监测糖尿病的发生、发展有着重要意义。 关键词 2型糖尿病 糖化血红蛋白（HbA1c） 影响因素 中图分类号：R587.1 文献标识码：C 文章编号：1006-1533（2012）12-0028-03 Analysis of HbA1c level and its related factors for community diabetic patients YANG Chun-feng, LIU Wen-bin, MA Xiao-feng, QU Lina, ZHANG Ming, XUE Wen-hong (Community Health Service Center of Wujiaochang Town, Yangpu District, Shanghai, 200433) ABSTRACT Objective：To learn the control status of glycosylated hemoglobin (HbA1c ) of type 2 diabetes patients in communities of shanghai, and Investigate the Possible factors, so as to provide evidence for diabetes management in community. Method: Selecting the diagnosed Type 2 diabetic patients from community, Measuring the height, body weight, blood pressure, waist and hip circumference, Testing blood glucose, blood lipids, and HbA1c etc. The patients were divided according to level of HbA1c as group A (HbA1c7.0% ) and group B (HbA1c≥7.0%). Retrospective analysis of factors that may affect glycosylated hemoglobin (HbA1c ) of type 2 diabetes patients was performed and the data were statistically analyzed with software package SPSS 9.13. Results: In group A the HbA1c level was correlated with the levels of body mass index (BMI), waist and hip circumference, fasting blood glucose (FBG), OGTT, and high density lipoprotein-cholesterol (HDL-C) and APOA (P 0.05). And in group B the HbA1c level was correlated with fasting blood glucose (FBG) and OGTT(P0.05). Conclusion: HbA1c May be affected with body weight, blood pressure, waist and hip circumference, fasting blood glucose, high density lipoprotein-ch