continuous versus bolus nasogastric tube feeding in premature neonates randomized controlled trial连续和丸鼻胃管喂养早产新生儿随机对照试验.pdfVIP

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continuous versus bolus nasogastric tube feeding in premature neonates randomized controlled trial连续和丸鼻胃管喂养早产新生儿随机对照试验.pdf

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continuous versus bolus nasogastric tube feeding in premature neonates randomized controlled trial连续和丸鼻胃管喂养早产新生儿随机对照试验

Open Journal of Pediatrics, 2012, 2, 214-218 OJPed /10.4236/ojped.2012.23034 Published Online September 2012 (http://www.SciRP.org/journal/ojped/) Continuous versus bolus nasogastric tube feeding in * premature neonates: Randomized controlled trial 1,2 1# 1 3 M. van der Star , Ben Semmekrot , Esmeralda Spanjaards , Anne Schaafsma 1Department of Pediatrics, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands 2University Medical Center St. Radboud, Nijmegen, The Netherlands 3FrieslandCampina, Innovation Infant Toddler Nutrition, Leeuwarden, The Netherlands Email: #b.semmekrot@cwz.nl Received 13 March 2012; revised 11 April 2012; accepted 28 May 2012 ABSTRACT 1. INTRODUCTION Background: Whether premature infants should be Most premature infants must initially be fed by gastric fed by bolus or continuous gavage feeding, is still a tube because of their inability to either suck effectively matter of debate. A recent Cochrane analysis re- or coordinate sucking, swallowing and breathing. vealed no difference. Study design and methods: We Several approaches exist as to tube feeding of preterm carried out a randomized controlled trial in prema- infants. An important difference in approach is whether ture infants on continuous versus bolus nasogastric to feed them continuously or by intermittent bolus. tube feeding, to search for differences with respect to