current status of sentinel node biopsy in urological malignancies当前状态的前哨淋巴结活检的泌尿系统恶性肿瘤.pdfVIP

current status of sentinel node biopsy in urological malignancies当前状态的前哨淋巴结活检的泌尿系统恶性肿瘤.pdf

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current status of sentinel node biopsy in urological malignancies当前状态的前哨淋巴结活检的泌尿系统恶性肿瘤

Vol.2, No.8, 836-841 (2010) HEALTH doi:10.4236/health.2010.28126 Current status of sentinel node biopsy in urological malignancies 1* 1 2 1 Alexander Winter , Jens Uphoff , Jens de la Roche , Friedhelm Wawroschek 1Department of Urology and Pediatric Urology, Hospital Oldenburg, Oldenburg, Germany; *Corresponding Author: winter.alexander@klinikum-oldenburg.de 2Institute of Nuclear Medicine, Hospital Oldenburg, Oldenburg, Germany Received 26 January 2010; revised 21 February 2010; accepted 23 February 2010. ABSTRACT mainly based upon the gained experiences of Cabanas in penile cancer. Seventeen years after the introduction of Like in most other malignancies the lymph node the term “sentinel lymph node” (SLN) in malignant tu- status is of outstanding prognostic relevance and an important tool for the determination of mors of the parotid gland by Gould [1], Cabanas postu- adjuvant strategies for urological tumor entities, lated a constant anatomically reproducible SLN for the too. Even in the era of PET/CT and MRI with iron penile cancer on the base of the classical lymphan- oxid nano-particles the radiological imaging giography [2]. Subsequent analysis however showed an technology is strongly limited in cases of me- individual variability for the SLN of the penile cancer as tastases smaller than 5 mm. Therefore only the well as for other tumors.

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