design of low-offset low-power cmos amplifier for biosensor application为生物传感器应用程序设计low-offset低功耗cmos放大器.pdfVIP

J. Biomedical Science and Engineering, 2009, 2, 538-542 JBiSE doi: 10.4236/jbise.2009.27078 Published Online November 2009 (http://www.SciRP.org/journal/jbise/). Design of low-offset low-power CMOS amplifier for biosensor application 1,2 1 2 Jin-Yong Zhang , Lei Wang , Bin Li 1Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; 2 School of Electronic and Information Engineering, South China University of Technology, Guangzhou, China. Email: jy.zhang@ ; wang.lei@ Received 19 June 2009; revised 10 July 2009; accepted 13 July 2009. ABSTRACT amplifying such weak signals requires an amplifier with low-offset and low-offset drift, which is quite challeng- A compacted and low-offset low-power CMOS am- ing without using any trimmed components. plifier for biosensor application is presented in this There are some techniques have been developed to paper. It includes a low offset Op-Amp and a high deal with the design challenges. Alternatively, auto-zero- precision current reference. With a novel continuous- ing (AZ), correlated double sampling (CDS) and chop- time DC offset rejection scheme, the IC achieves pe