原创力文档dose-dependent effects of pentabrominated diphenyl ethers on sexual hormone and histology of male reproductive system in rats剂量依赖性pentabrominated二苯醚对性荷尔蒙和组织学的影响男性生殖系统的老鼠.pdfVIP
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dose-dependent effects of pentabrominated diphenyl ethers on sexual hormone and histology of male reproductive system in rats剂量依赖性pentabrominated二苯醚对性荷尔蒙和组织学的影响男性生殖系统的老鼠
J. Biomedical Science and Engineering, 2012, 5, 302-306 JBiSE
/ 10.4236/jbise.2012.56039 Published Online June 2012 (http://www.SciRP.org/journal/jbise/)
Dose-dependent effects of pentabrominated diphenyl ethers
on sexual hormone and histology of male reproductive
system in rats
*
Lingyan Yuan, Meiqing Fan, Ping Zhan
Department of Environment Hygiene, Chongqing Medical University, Chongqing, China
*
Email: zanpingcqums@163.com
Received March 22nd, 2012; revised April 9th, 2012; accepted April 13th, 2012
ABSTRACT mulation, PBDEs are regarded as ubiquitously occurring
environmental contaminants [2]. PBDEs have been iden-
Polybrominated diphenyl ethers (PBDEs) used as flame
tified in various environmental sectors, including air,
retardants are widely used in a variety of consumer
sewage sludge and sediment [3], biota including fish [4],
products, like textiles, foam and building materials.
mussels [5], fish-eating birds and marine mammals [6].
They are persistent in the environment, and increas-
PBDEs have also been identified in human adipose tissue,
ing levels of PBDEs have been found both biota and
breast milk and blood [7]. Fetuses and newborns have
human tissue samples. In the present study we exa-
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