effects of change in smoking habits on bladder cancer incidence in tunisia改变吸烟习惯对膀胱癌发病率的影响在突尼斯.pdfVIP

Vol.3, No.10, 613-619 (2011) Health doi:10.4236/health.2011.310103 Effects of change in smoking habits on bladder cancer incidence in Tunisia 1 1,2 3 4 1* Dhafer Mrizak , Fatma Bchir , Mehdi Jaidane , Maurice Jean Arnaud , Saâd Saguem 1Metabolic Biophysics and Applied Pharmacology Laboratory, Department of Biophysics, Medicine Faculty of Sousse, Sousse, * Tunisia; Corresponding Author: bchirfatma@hotmail.fr 2Laboratory of Natural Substances, National Institute of Research and Physical Chemical Analysis, Technopole Sidi Thabet, Tunisia; 3Urolology Department of Central Hospital University (CHU), Sahloul-Sousse, Tunisia; 4Nutrition Biochemistry, Bourg Dessous 2A, La Tour de Peilz, Switzerland. Received 22 January 2011; revised 19 February 2011; accepted 28, February 2011. ABSTRACT tobacco smoking [4,5]. Although stabilization and even decrease frequencies Bladder cancer is among the most frequently of major cancers types which are associated to smoking diagnosed cancer. Tobacco smoking exposures such as lung cancer and oral cavity cancer, a dramatic involving nitrosamines and aromatic amines increase in the incidence of bladder cancer was regis- are the main cause of bladder cancer. Although tered in Tunisian Cancer Centers for t