原创力文档efficacy of static magnetic field for pain of adjuvant arthritis rats功效的静态磁场对大鼠佐剂关节炎的痛苦.pdfVIP
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efficacy of static magnetic field for pain of adjuvant arthritis rats功效的静态磁场对大鼠佐剂关节炎的痛苦
Advances in Bioscience and Biotechnology, 2012, 3, 511-515 ABB
/10.4236/abb.2012.324067 Published Online August 2012 (http://www.SciRP.org/journal/abb/)
Efficacy of static magnetic field for pain of adjuvant
arthritis rats
1 1,2
Shigeyuki Kanai , Norimasa Taniguchi
1Department of Physical Therapy, Faculty of Health Science, Kansai University of Health Science, Osaka, Japan
2Research Section for Magnetics, Product Development Department, Development Division, PIP Co, Ltd, Osaka, Japan
Email: n-taniguchi@pipjapan.co.jp, kanai@kansai.ac.jp
Received 29 June 2012; revised 30 July 2012; accepted 13 August 2012
ABSTRACT to be clinically effective.
Adjuvant arthritis (AA) in the rat is an excellent model
Rats suffering from adjuvant arthritis (AA) were
of acute periarticular proliferative synovitis and is in-
used to examine the effect of a static magnetic field
duced by a single intradermal injection of tubercle bacil-
(SMF) upon pain relief. Rats were divided into SMF-
lus to the hind paw [17]. As one of the main experiment-
treated AA rats, non-SMF treated AA rats and con-
tal models of arthritis, AA rats have been used to evalu-
trol rats. Following SMF stimulation, we measured
ate the efficacy of several drugs at many inst
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