原创力文档acute hyperglycemia does not impair microvascular reactivity and endothelial function during hyperinsulinemic isoglycemic and hyperglycemic clamp in type 1 diabetic patients急性高血糖不损害微血管反应和内皮功能在血糖isoglycemic和高血糖的夹在1型糖尿病患者.pdfVIP
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acute hyperglycemia does not impair microvascular reactivity and endothelial function during hyperinsulinemic isoglycemic and hyperglycemic clamp in type 1 diabetic patients急性高血糖不损害微血管反应和内皮功能在血糖isoglycemic和高血糖的夹在1型糖尿病患者
Hindawi Publishing Corporation
Experimental Diabetes Research
Volume 2012, Article ID 851487, 8 pages
doi:10.1155/2012/851487
Clinical Study
Acute Hyperglycemia Does Not Impair Microvascular Reactivity
and Endothelial Function during Hyperinsulinemic Isoglycemic
and Hyperglycemic Clamp in Type 1 Diabetic Patients
1 2 1 2 1
ˇ
´ ˇ´ ˇ ´ ˇ
Eva Horova, Jirı Mazoch, Jirina HiIgertova, Jan Kvasnicka, Jan Skrha,
1 1
ˇ
´ ´
Jan Soupal, and Martin Prazny
1 3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, U Nemocnice 1, 12800 Prague, Czech Republic
2 Department of Hematology, 1st Faculty of Medicine, Charles University, U Nemocnice 2, 12800 Prague, Czech Republic
´ ´
Correspondence should be addressed to Martin Prazny, mpra@lf1.cuni.cz
Received 13 July 2011; Accepted 22 September 2011
Academic Editor: Bernard Portha
´
Copyright © 2012 Eva Horova et al. This is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Aims . The aim of this study was to evaluate the effect of acute glycemia increase on microvasculature and endothelium in Type 1
diabetes during hyperin
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