antioxidant activity of iranian echium amoenum fisch c.a. mey flower decoction in humans a cross-sectional beforeafter clinical trial抗氧化活性的伊朗echium amoenum fisch c.a mey花汤人类横断面beforeafter临床试验.pdfVIP
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antioxidantactivityofiranianechiumamoenumfisch
Advance Access Publication 26 May 2006 eCAM 2006;3(4)469–473
doi:10.1093/ecam/nel031
Original Article
Antioxidant Activity of Iranian Echium amoenum Fisch
C.A. Mey Flower Decoction in Humans: A cross-sectional
Before/After Clinical Trial
1 1 1 1
Akram Ranjbar , Sara Khorami , Mehdi Safarabadi , Amene Shahmoradi ,
1 1 2,3 3
Ali Akbar Malekirad , Katyon Vakilian , Ali Mandegary and Mohammad Abdollahi
1Arak University of Medical Sciences, Arak, 2 Faculty of Pharmacy, Kerman University of Medical Sciences,
Kerman and 3Faculty of Pharmacy, Pharmaceutical Sciences Research Center,
Tehran University of Medical Sciences, Tehran, Iran
Medicinal plants are recognized as sources of natural antioxidants that can protect from biological
system oxidative stress. The present cross-sectional before/after clinical trial was carried out to investi-
gate the antioxidant properties of the decoction of the flowers of Echium amoenum Fisch C.A. Mey in
humans. A group of 38 healthy subjects was invited to use the E. amoenum (7 mg kg1) twice daily for
14 days. Blood samples before and after entering the study were measured for lipid peroxidation level
(LPO), total antioxidant capacity (TAC) and total thiol (SH) molecules. A significant reduction of blood
LPO (24.65 ± 11.3 versus 19.05 ± 9
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