brain activity stimulated by prism adaptation tasks utilized for the treatment of unilateral spatial neglect a study with fnirs大脑活动刺激通过棱镜适应任务用于治疗单侧空间忽略fnirs的研究.pdfVIP

Hindawi Publishing Corporation Rehabilitation Research and Practice Volume 2012, Article ID 312781, 6 pages doi:10.1155/2012/312781 Clinical Study Brain Activity Stimulated by Prism Adaptation Tasks Utilized for the Treatment of Unilateral Spatial Neglect: A Study with fNIRS Hiroshi Taniguchi,1 Makoto Hiyamizu,1 Takanori Tominaga,2 and Shu Morioka1 1 Department of Neurorehabilitation, Graduate School of Health Science, Kio University, 4-2-2 Umami-naka koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan 2 Department of Rehabilitation, Murata Hospital, 4-2-1 Tashima-cho Ikuno-ku Osaka 544-0011, Japan Correspondence should be addressed to Hiroshi Taniguchi, manato719@yahoo.co.jp Received 1 December 2011; Revised 18 January 2012; Accepted 1 February 2012 Academic Editor: K. S. Sunnerhagen Copyright © 2012 Hiroshi Taniguchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We investigated the neurological basis for efficacy of prism adaptation therapy, which is used for the treatment of poststroke unilateral spatial neglect (USN). Study subjects were 6 USN-positive (+), 6 USN-negative patients, and 6 healthy volunteer control subjects. USN was identified by the Behavioural Inattention Test (BIT). During the tasks, brain activity was assessed with fNIRS via changes in oxyHb concentration per unit length. There was no significant difference in the number of errors in the task between the 3 groups. However, in the USN(+) group there was a significantly greater reduction in oxyHb levels in the right parietal association cortex during the prism adaptation task than in the other 2 groups (P 0.05). There was an immedi