serum adiponectin levels in different phenotypes of polycystic ovary syndrome血清脂联素水平在不同表型的多囊卵巢综合征.pdf

Open Journal of Endocrine and Metabolic Diseases, 2012, 2, 125-131 /10.4236/ojemd.2012.24019 Published Online November 2012 (http://www.SciRP.org/journal/ojemd) Serum Adiponectin Levels in Different Phenotypes of Polycystic Ovary Syndrome 1 1 2 3 Carolina Fux Otta , Paula Szafryk de Mereshian , Raquel Kaplan , Gabriel Santino Iraci , Silvia Ojeda4 5 6 6 2 , José Ochoa , Andrés Albrecht , Natalia Filipone , Marta Fiol de Cuneo 1Departamento de Endocrinología y Diabetes, Hospital Universitario de Maternidad y Neonatología (HUM y N), Córdoba, Argentina 2Cátedra de Fisiología Humana, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba (UNC), Córdoba, Argentina 3Cátedra de Farmacología Aplicada, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba (UNC), Córdoba, Argentina 4Grupo de Probabilidad y Estadística, Facultad de Matemática, Astronomía y Física (UNC), Córdoba, Argentina 5Diangus, Diagnóstico por Imágenes, Docencia e Investigación, Córdoba, Argentina 6Laboratorio MEGA, Rafaela, Argentina Email: endofux@.ar Received August 20, 2012; revised September 22, 2012; accepted October 25, 2012 ABSTRACT Objectives: to evaluate and compare serum adiponectin levels in different phenotypes of polycystic ovary syndrome (PCOS) and to investigate their correlation with endocrine and metabolic parameters. Material and methods: we studied 5 groups of patients: A (n = 20): H (hyperandrogenism) + O (oligoanovulation) + P (polycystic ovary) [classic phenotype]; B