谷康泰灵对骨代谢影响的临床观察（Clinical observation of the effect of Gu Kangtai Ling on bone metabolism）.docVIP

谷康泰灵对骨代谢影响的临床观察（Clinical observation of the effect of Gu Kangtai Ling on bone metabolism） Clinical observation of the effect of Gu Kangtai Ling on bone metabolism Update Date: 2009-07-15 Click: Chen Baicheng, Zhang Jing, Ge Li Abstract: in order to explore the pathogenesis of osteoporosis, and Tani Yasutai Ling Injection treatment, the valley of Kang Tailing injection daily intramuscular injection of 2ml, a total of 20 days after the injection, observation of urinary type I collagen peptide (CrossLaps) and special blood Osteocalcin (BGP) changes and the clinical efficacy was compared between groups. Results showed that the content of the treatment group in the urine of Cross Laps before and after treatment, decreased significantly, with statistical significance (P 0.05); the content of BGP in blood after treatment was significantly higher than that before treatment, there were significant differences (P 0.05); the control group had no change. The analysis suggested that Gu Kangtai Ling may be a series of clinical syndrome groups by inhibiting osteoclast activity, promoting osteoblast synthesis and increasing bone mass to alleviate osteoporosis. Subject headings osteoporosis / therapy, Kangtai, Ling / therapeutic use, osteocalcin / blood collagen, I, CrossLaps/ urine CLC number: R969.1, document identification code: A, article number: 1001-6015 (2000) 06-0012-02 THE, CLINICAL, SIGNIFICANCE, OF, THE, INFLUENCE, OF, GUKANGTAI, LING, ON, BONE, METABOLISM Chen, Baicheng, Zhang, Jing, Ge, Li (Orthopedic, Institute, of, Hebei, Province, Shijiazhuang, 050051) 骨质疏松症是由“gukangtai灵治疗”（gktl）注射液（2毫升/天肌内注射）20天来探讨骨质疏松症的发病机制，骨代谢疾病，和gktl注射液疗效。治疗后，在Ⅰ的C端肽型胶原的变化（变化）在尿液和骨钙素（BGP）血液中进行观察，并对两组的临床疗效进行比较。结果表明，治疗组水平明显降低，I型胶原C端肽（P＜0.05），而BGP水平明显升高（P＜0.05）在前和后的疗效比较。然而，变化和BGP的对照组无变化。gktl可以免除一系列临床综合征组骨质疏松引起的通过抑制破骨细胞活性，促进成骨细胞的合成，从而增加骨量。 关键词：骨质疏松症/治疗“顾康泰玲”/治疗应用骨钙素/血液Ⅰ型胶原蛋白胶原蛋白/尿 骨形态发生蛋白（BMP）做为一种诱导成骨因子已被众多学者所共识。而且通过实验证实，它能诱导未分化间充质细胞不可逆的分化形成软骨和骨，从而导致新骨形成〔1〕。谷康泰灵注射液主要成份为BMP和多种骨生长因子，以及多种微量元素，可以用来补充体内所