硫酸镁和酚妥拉明复合注射液治疗肺心病伴心衰效果研究.docVIP

硫酸镁和酚妥拉明复合注射液治疗肺心病伴心衰效果研究[摘　要]　目的：硫酸镁与酚妥拉明复合注射液治疗肺源性心脏病伴心力衰竭的临床疗效。方法：回顾性分析我院收治的90例肺心病伴心衰患者的临床资料，随机分为治疗组及对照组，各45例，两组患者均采取常规治疗，治疗组患者加用硫酸镁与酚妥拉明复合注射液，随访3个月，治疗前后对患者行心脏彩色多普勒超声检查，比较两组患者的临床疗效及心脏功能各指标变化情况。结果：治疗组患者临床疗效及心脏各指标改善优于对照组，两组患者比较差异有统计学意义（p＜0.05）。结论：硫酸镁与酚妥拉明复合注射液能明显改善改善患者心脏功能及临床症状，效果满意，值得在临床推广。 [关键词]　硫酸镁与酚妥拉明复合注射液；慢性肺源性心脏病；心力衰竭；心功能；临床疗效 [Abstract] Objective ：Magnesium sulfate and phentolamine injection therapy combined with pulmonary heart disease， heart failure clinical efficacy. Methods： A retrospective analysis of our hospital 90 patients with pulmonary heart disease with clinical data of patients with heart failure were randomly divided into treatment group and control group， all 45 cases， two groups of patients were taking conventional treatment， patients treated with magnesium sulfate was added compound phentolamine injection， followed 3 months after treatment of patients with cardiac color Doppler ultrasound examination were compared the clinical efficacy and cardiac function changes in each index. Results： The clinical efficacy and improved cardiac index than the control group， two groups of patients the difference was statistically significant （p ＜0.05）. Conclusion： Magnesium sulfate and phentolamine combined injection can significantly improve cardiac function and improve clinical symptoms in patients with satisfactory results， it is worth in clinical practice. [Key Words] magnesium sulfate and phentolamine combined injection chronic pulmonary heart disease heart failure heart function clinical efficacy 慢性肺心病是因为肺、肺血管、胸廓疾病引起的肺循环阻力增加，肺动脉高压，进而引起右心室肥厚、扩大甚至发生右心衰竭的心脏病[1]，多数学者认为肺心病合并心衰患者的治疗以卧床休息、氧疗、改善呼吸功能、糾正低氧血症、解除二氧化碳潴留，心理衰竭可减轻或缓解，但是部分患者经治疗后心功能不能得到改善。本文介绍我院在常规治疗的基础上加用硫酸镁与酚妥拉明复合注射液治疗慢性肺心病合并心衰，效果满意，现报告如下： 1　资料和方法 1.1一般资料　回顾性分析我院2008年9月～2011年7月收治的90例肺心病伴心衰患者的临床资料，随机分为治疗组及对照组，各45例，治疗组男性24例，女性21例，年龄在54～73岁，心功能NYHAⅢ级34例，Ⅳ11例；对照组男性25例，女性20例，年龄在55～75岁之间，心功能NYHAⅢ级30例，Ⅳ15例。两组患者在年龄、性别、心功能分级等方面比较差异无统计学意义（p＞0.05）。 1.2方法　两组患者均按照常规治疗，卧床休息。持续低流量吸氧、低盐饮食、适当应用强心剂、利尿剂。治