base-pair resolution dna methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia碱基对决议dna甲基化测序揭示深刻的不同表观遗传景观在急性髓系白血病.pdfVIP

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia 1. 2. 3 2 4 Altuna Akalin , Francine E. Garrett-Bakelman , Matthias Kormaksson , Jennifer Busuttil , Lu Zhang , 4 5 6 7 6 Irina Khrebtukova , Thomas A. Milne , Yongsheng Huang , Debabrata Biswas , Jay L. Hess , C. 7 8 9 ¨ 9 9 10 David Allis , Robert G. Roeder , Peter J. M. Valk , Bob Lowenberg , Ruud Delwel , Hugo F. Fernandez , 11 12 4 1 2,13 Elisabeth Paietta , Martin S. Tallman , Gary P. Schroth , Christopher E. Mason *, Ari Melnick *, Maria E. Figueroa6* 1 Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America, 2 Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medical College, New York, New York, United States of America, 3 Department of Public Health, Weill Cornell Medical College, New York, New York, United States of America, 4 Illumina, Hayward, California, United States of America, 5 MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom, 6 Department of