brain structural correlates of reward sensitivity and impulsivity in adolescents with normal and excess weight大脑结构相关奖励敏感性和冲动与正常青少年和多余的体重.pdfVIP

Brain Structural Correlates of Reward Sensitivity and Impulsivity in Adolescents with Normal and Excess Weight ´ 1 2,3 1 4 Laura Moreno-Lopez , Carles Soriano-Mas , Elena Delgado-Rico , Jacqueline S. Rio-Valle , ´ 1,5* Antonio Verdejo-Garcıa 1 Department of Personality, Evaluation and Psychological Treatment, University of Granada, Granada, Spain, 2 Department of Psychiatry, Bellvitge University Hospital- ´ ´ IDIBELL, Barcelona, Spain, 3 Carlos III Health Institute, Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Granada, Spain, 4 Department of Nursing, ´ University of Granada, Granada, Spain, 5 Institute of Neurosciences Federico Oloriz, University of Granada, Granada, Spain Abstract Introduction: Neuroscience evidence suggests that adolescent obesity is linked to brain dysfunctions associated with enhanced reward and somatosensory processing and reduced impulse control during food processing. Comparatively less is known about the role of more stable brain structural measures and their link to personality traits and neuropsychological factors on the presentation of adolescent obesity. Here we aimed to investigate regional brain anatomy in adolescents with excess weight vs. lean controls. We also aimed to contrast the associations between brain structure and personality and cognitive measures in both groups. Methods: Fifty-two adolescents