characteristics of suicide attempts in anorexia and bulimia nervosa a case–control study特征的自杀企图厌食症和暴食症病例对照研究.pdfVIP

Characteristics of Suicide Attempts in Anorexia and Bulimia Nervosa: A Case–Control Study ´ 1,2,3,4 1 ´ 1,3 1 5 Sebastien Guillaume *, Isabelle Jaussent , Emilie Olie , Catherine Genty , Jacques Bringer , Philippe Courtet1,2,3, Ulrike Schmidt4 ´ ˆ 1 Inserm, U1061, Montpellier, France, 2 Universite Montpellier I, Montpellier, France, 3 CHU Montpellier, Hopital Lapeyronie, Psychiatric Emergency and Post Emergency Department, Pole Urgence, Montpellier, France, 4 King’s College London, Institute of Psychiatry, London, United Kingdom, 5 Endocrinology Department, CHU Montpellier, Montpellier, France Abstract Objective: Compared to other eating disorders, anorexia nervosa (AN) has the highest rates of completed suicide whereas suicide attempt rates are similar or lower than in bulimia nervosa (BN). Attempted suicide is a key predictor of suicide, thus this mismatch is intriguing. We sought to explore whether the clinical characteristics of suicidal acts differ between suicide attempters with AN, BN or without an eating disorders (ED). Method: Case-control study in a cohort of suicide attempters (n = 1563). Forty-four patients with AN and 71 with BN were compared with 235 non-ED attempters matched for sex, age and education, using interview measures of suicidal intent and severity. Results: AN patients were more likely to have made a serious attempt (OR = 3.4, 95% CI 1.4–7.9), with a higher expectation of dying (OR = 3.7,95% CI 1.1–13.5), and an increased risk of severity (OR = 3.4,95% CI 1.2–9.6). BN patients did not differ from the control group. Clinical markers of the severity of ED were associated wit