chronic maternal depression is associated with reduced weight gain in latino infants from birth to 2 years of age慢性母亲抑郁与减少体重增加在拉丁裔婴儿从出生到2岁.pdfVIP

Chronic Maternal Depression Is Associated with Reduced Weight Gain in Latino Infants from Birth to 2 Years of Age 1 1 2 4 3 Janet M. Wojcicki *, Katherine Holbrook , Robert H. Lustig , Elissa Epel , Aaron B. Caughey , Ricardo F. ˜ 4 5 1 Munoz , Stephen C. Shiboski , Melvin B. Heyman 1 Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, University of California San Francisco, San Francisco, California, United States of America, 2 Division of Pediatric Endocrinology, Department of Pediatrics, University of California San Francisco, San Francisco, California, United States of America, 3 Department of Obstetrics and Gynecology, University of California San Francisco, San Francisco, California, United States of America, 4 Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America, 5 Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America Abstract Background: Latino children are at increased risk for mirconutrient deficiencies and problems of overweight and obesity. Exposures in pregnancy and early postpartum may impact future growth trajectories. Objectives: To evaluate the relationship between prenatal and postnatal maternal depressive symptoms experienced in pregnancy and infant growth from birth to 2 years of age in a cohort of Latino infants. Methods: We recruited pregnant Latina mothers at two San Francisco hospitals and followed their healthy infants to 24 months of age. At 6, 12 and 24 months of age, infants were weighed and measured. Maternal depressive symptoms were assessed prenatally and at 4-6 weeks postpartum. W