dominance of hiv-1 subtype crf01_ae in sexually acquired cases leads to a new epidemic in yunnan province of china主导地位的hiv - 1亚型crf01_ae性收购的情况下会导致一个新的流行中国的云南省.pdfVIP

PLoS MEDICINE Dominance of HIV-1 Subtype CRF01_AE in Sexually Acquired Cases Leads to a New Epidemic in Yunnan Province of China 1 1 2 2,3 1 1 3 2 1 1 Yong Zhang , Lin Lu , Lei Ba , Li Liu , Li Yang , Manhong Jia , Haibo Wang , Qing Fang , Yuhua Shi , Wenyun Yan , Guangcai Chang1 2,3 2 2,3* , Linqi Zhang , David D. Ho , Zhiwei Chen 1 Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, People’s Republic of China, 2 Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, United States of America, 3 State Key Laboratory of Virology, Modern Virology Research Center and AIDS Center, Wuhan University, Wuhan, Hubei, People’s Republic of China Funding: We thank International A B S T R A C T AIDS Vaccine Initiative, Irene Diamond Fund, China AIDS Initiatives, and NIH grant R01HL080211 (to ZC) for their Background support. The funders had no role in study design, data collection and Dating back to the first epidemic among injection drug users in 1989, the Yunnan province analysis, decision to publish, or has had the highest number of human immunodeficiency virus type 1 (HIV-1) infections in preparation of the manuscript. China. However, the molecular epidemiology of HIV-1 in Yunnan has not been fully Competing Interests: The authors characterized. have declared that no competing interests exist. Methods and Findings Academic Editor: Chris