effect of artemether-lumefantrine policy and improved vector control on malaria burden in kwazulu–natal, south africa蒿甲醚的影响苯芴醇政策和改进的矢量控制疟疾负担在夸祖鲁-纳塔尔省,南非.pdfVIP

Open access, freely available online PLoS MEDICINE Effect of Artemether-Lumefantrine Policy and Improved Vector Control on Malaria Burden in KwaZulu–Natal, South Africa 1* 2 1,3 4 1 1 Karen I. Barnes , David N. Durrheim , Francesca Little , Amanda Jackson , Ushma Mehta , Elizabeth Allen , Sicelo S. Dlamini4 4 4 5 6,7 4 , Joyce Tsoka , Barry Bredenkamp , D. Jotham Mthembu , Nicholas J. White , Brian L. Sharp 1 Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa, 2 Health Protection, Hunter New England Population Health, Newcastle, New South Wales, Australia, 3 Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa, 4 Malaria Research Lead Programme, Medical Research Council, Durban, South Africa, 5 Malaria Control Programme, KwaZulu–Natal Provincial Department of Health, South Africa, 6 Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, 7 Centre of Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom Competing Interests: NJW is A B S T R A C T chairman of the World Health Organization malaria treatment Background guidelines committee and is on the editorial board of PLoS medicine. The authors have no other conflict of Between 1995 and 2000, KwaZulu–Natal province, South Africa, experienced a marked interest to declare. increase in Plasmodium falciparum malaria, fu